Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.62 |
| ▸ | CA6 | P23280 | 4/20 | 0.62 |
| ▸ | CA7 | P43166 | 4/20 | 0.62 |
| ▸ | CA9 | Q16790 | 4/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | CA4 | P22748 | 3/20 | 0.62 |
| ▸ | CA5A | P35218 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.62 |
| ▸ | F13A1 | P00488 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | THPO | P40225 | 2/20 | 0.62 |
| ▸ | CA3 | P07451 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21434318 | 0.95 | CA12 (0.62) | CA12CA6CA7CA9CA14 | |
| SCHEMBL7991030 | 0.95 | TDP1 (0.58) | CA12CA6CA7CA9CA14 | |
| SCHEMBL16360723 | 0.93 | ALOX15 (0.55) | CA12CA6CA7CA9CA14 | |
| SCHEMBL29225286 | 0.93 | ALOX15 (0.59) | CA12CA6CA7CA9CA14 | |
| SCHEMBL832891 | 0.92 | TDP1 (0.62) | CA12CA6CA7CA9CA14 | |
| SCHEMBL12827888 | 0.92 | TDP1 (0.56) | CA12CA6CA7CA9CA14 | |
| SCHEMBL13336449 | 0.90 | CA12 (0.65) | CA12CA6CA7CA9CA14 | |
| SCHEMBL12520087 | 0.88 | TDP1 (0.58) | CA12CA6CA7CA9CA14 | |
| SCHEMBL30667454 | 0.88 | CA12 (0.62) | CA12CA6CA7CA9CA14 | |
| SCHEMBL19179134 | 0.88 | TDP1 (0.58) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1342413-A1 | Plant protection formulation containing a copper-polyamine chelate | BMS Micro-Nutrients N.V. (BE) | 2003-09-10 | — | — | EP | claimed |
| US-6172261-B1 | BIOSYNTHESIS USING CHAIN EXTENSION | ORIDIGM CORPORATION | 2001-01-09 | — | — | US | claimed |
| EP-1001927-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003823-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 1999-01-28 | — | — | WO | claimed |
| EP-1867633-A1 | Polyamine analogues as therapeutic and diagnostic agents | MediQuest Therapeutics, Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| US-7208528-B1 | Polyamine analogues as therapeutic and diagnostic agents | MEDIQUEST THERAPEUTICS, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-7160923-B1 | Polyamine analogues as therapeutic and diagnostic agents | MEDIQUEST THERAPEUTICS, INC. (US) | 2007-01-09 | — | — | US | disclosed |
| EP-1296931-B1 | POLYAMINE ANALOGUES AS CYTOTOXIC AGENTS | MEDIQUEST THERAPEUTICS INC (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1342413-B1 | Plant protection formulation containing a copper-polyamine chelate | BMS MICRO NUTRIENTS N V (BE) | 2005-08-24 | — | — | EP | disclosed |
| US-6872852-B2 | Polyamine analogues as cytotoxic agents | MEDIQUEST THERAPEUTICS, INC. (US) | 2005-03-29 | — | — | US | disclosed |
| US-6646149-B1 | Derivitives of spermine or its N12-t-butyl carbamate | VERMEULIN NICOLAAS M J (US) | 2003-11-11 | — | — | US | disclosed |
| EP-1342413-A1 | Plant protection formulation containing a copper-polyamine chelate | BMS Micro-Nutrients N.V. (BE) | 2003-09-10 | — | — | EP | disclosed |
| US-20030045755-A1 | Polyamine analogues as cytotoxic agents | MEDIQUEST THERAPEUTICS, INC. | 2003-03-06 | — | — | US | disclosed |
| WO-2001072685-A9 | POLYAMINE ANALOGUES AS CYTOTOXIC AGENTS | ORIDIGM CORP (US) | 2002-10-10 | — | — | WO | disclosed |
| WO-2001092218-A2 | POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 2001-12-06 | — | — | WO | disclosed |
| EP-1085011-A1 | Novel polyamine analogues as therapeutic and diagnostic agents | ORIDIGM CORPORATION (US) | 2001-03-21 | — | — | EP | disclosed |
| US-6172261-B1 | BIOSYNTHESIS USING CHAIN EXTENSION | ORIDIGM CORPORATION | 2001-01-09 | — | — | US | disclosed |
| EP-1001927-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999003823-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 1999-01-28 | — | — | WO | disclosed |
| EP-0162413-A2 | Polyamine for use as a medicine in the treatment of neoplasms | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-11-27 | — | — | EP | disclosed |