Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL156717 | 0.88 | TSHR (0.48) | TSHRHPGDALDH1A1HCAR2THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL9818307 | 0.88 | TSHR (0.48) | TSHRHPGDALDH1A1HCAR2THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL9069456 | 0.88 | TSHR (0.48) | TSHRHPGDALDH1A1HCAR2THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL27623718 | 0.86 | TSHR (0.47) | TSHRHPGDALDH1A1HCAR2THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL5860506 | 0.86 | TSHR (0.47) | TSHRHPGDALDH1A1HCAR2THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL10809888 | 0.86 | TSHR (0.47) | TSHRHPGDALDH1A1HCAR2THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL29290957 | 0.84 | TSHR (0.46) | TSHRHPGDALDH1A1HCAR2THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL3440750 | 0.84 | HCAR2 (0.48) | TSHRHPGDALDH1A1HCAR2THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL564981 | 0.84 | TSHR (0.40) | TSHRHPGDALDH1A1HCAR2THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL26669182 | 0.83 | TSHR (0.44) | TSHRHPGDALDH1A1HCAR2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294152-B2 | Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound | L'OREAL S.A. (FR) | 2007-11-13 | — | — | US | disclosed |
| US-20050188475-A1 | Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound | L'OREAL S.A. (FR) | 2005-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050188475-A1 | Dyeing composition comprising at least one fluorindine compound for the dyeing of keratinic fibers, dyeing process comprising the composition and compound | KRT18, FLNA, FLNB | TSHR 4783/4885HPGD 717/4885ALDH1A1 564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.