SCHEMBL5360967

SCHEMBL5360967

CCCCCCCCCCCCCC(CC=O)C(CCCC=O)CCCCCCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
FAAH O00519 2/20 0.50
TRPV1 Q8NER1 2/20 0.50
ADH1B P00325 2/20 0.40
ADH1C P00326 2/20 0.40
ADH1A P07327 2/20 0.40
ADH4 P08319 2/20 0.40
ADH7 P40394 2/20 0.40
EPHX1 P07099 1/20 0.38
DNM1 Q05193 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
CA2 P00918 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TRPA1 O75762 1/20 0.35
DDAH1 O94760 1/20 0.35
GAPDH P04406 1/20 0.35
MAPT P10636 1/20 0.35
FDPS P14324 3/20 0.34
GPR84 Q9NQS5 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18803115 0.88 TSHR (0.73) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL27928140 0.88 TSHR (0.73) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL14474297 0.88 TSHR (0.73) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL1754916 0.88 TSHR (0.73) TSHRFAAHTRPV1ADH1BADH1C
Hydrochloric Acid SCHEMBL1358842 0.86 TSHR (0.70) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL25907690 0.79 TSHR (0.65) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL9425832 0.79 TSHR (0.65) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL6862076 0.79 TSHR (0.58) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL1035441 0.79 TSHR (0.65) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL11765099 0.78 TSHR (0.62) TSHRFAAHTRPV1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169765-B1 Acyl deoxyribonucleoside derivatives and uses thereof WELLSTAT THERAPEUTICS CORPORATION (US) 2007-01-30 US disclosed
EP-0712629-B1 Acyl deoxyribonucleoside derivatives and uses thereof WELLSTAT THERAPEUTICS CORP (US) 2003-06-18 EP disclosed
US-6348451-B1 WOUND HEALING AGENTS FOR ANIMALS PRO-NEURON, INC. 2002-02-19 US disclosed
US-6306834-B1 METHODS OF TREATING OR PREVENTING RADIATION, MUTAGEN AND SUNLIGHT-INDUCED BIOLOGICAL DAMAGE, METHODS FOR IMPROVING WOUND HEALING AND TISSUE REPAIR, COMPRISING ADMINISTERING THE COMPOSITIONS OF THE PRESENT INVENTION TO AN ANIMAL. PRO-NEURON, INC. 2001-10-23 US disclosed
US-6297222-B1 TREATING OR PREVENTING RADIATION, MUTAGEN AND SUNLIGHT-INDUCED BIOLOGICAL DAMAGE, AND METHODS FOR IMPROVING WOUND HEALING AND TISSUE REPAIR PRO-NEURON, INC. 2001-10-02 US disclosed
US-6103701-A ADMINISTERING COMPOSITIONS COMPRISING ACYL DERIVATIVES OF 2'-DEOXYRIBONUCLEOSIDES; FOR IMPROVING WOUND HEALING AND TISSUE REPAIR VON BORSTEL REID WARREN (US) 2000-08-15 US disclosed
US-6020322-A Acyl deoxyribonucleoside derivatives and uses thereof PRO-NEURON, INC. (US) 2000-02-01 US disclosed
EP-0355131-B1 ACYL DEOXYRIBONUCLEOSIDE DERIVATIVES AND USES THEREOF PRO NEURON INC (US) 1996-09-04 EP disclosed
EP-0712629-A1 Acyl deoxyribonucleoside derivatives and uses thereof PRO-NEURON, INC. (US) 1996-05-22 EP disclosed
EP-0355131-A1 ACYL DEOXYRIBONUCLEOSIDE DERIVATIVES AND USES THEREOF PRO-NEURON, INC. (US) 1990-02-28 EP disclosed