Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 4/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.49 |
| ▸ | CHRNG | P07510 | 2/20 | 0.49 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.49 |
| ▸ | CHRND | Q07001 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14359605 | 0.85 | CHRNB2 (0.63) | MMP2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12085491 | 0.85 | CHRNB2 (0.63) | MMP2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Phenylalanine Amide SCHEMBL353251 | 0.82 | SLC7A5 (0.73) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL244302 | 0.82 | SLC7A5 (0.73) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL244303 | 0.82 | SLC7A5 (0.73) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL11349868 | 0.82 | SLC7A5 (0.73) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL23002157 | 0.81 | SLC7A5 (0.70) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL11569548 | 0.81 | SLC7A5 (0.70) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL353593 | 0.81 | SLC7A5 (0.70) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL31657718 | 0.81 | SLC7A5 (0.70) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208528-B1 | Polyamine analogues as therapeutic and diagnostic agents | MEDIQUEST THERAPEUTICS, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| EP-1085011-A1 | Novel polyamine analogues as therapeutic and diagnostic agents | ORIDIGM CORPORATION (US) | 2001-03-21 | — | — | EP | disclosed |