Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505255 | 0.91 | DHODH (0.69) | DHODHHDAC6 | |
| SCHEMBL505241 | 0.89 | DHODH (0.68) | DHODH | |
| SCHEMBL536113 | 0.85 | DHODH (0.58) | DHODHHDAC6 | |
| SCHEMBL536117 | 0.85 | DHODH (0.60) | DHODHHDAC6 | |
| SCHEMBL505568 | 0.83 | DHODH (0.70) | DHODHHDAC6 | |
| SCHEMBL536118 | 0.83 | DHODH (0.52) | DHODH | |
| SCHEMBL505388 | 0.83 | DHODH (1.00) | DHODH | |
| SCHEMBL10212238 | 0.82 | DHODH (0.64) | DHODH | |
| SCHEMBL505932 | 0.82 | DHODH (0.71) | DHODHHDAC6 | |
| SCHEMBL505320 | 0.79 | DHODH (0.70) | DHODHHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414328-A2 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | Merck Serono S.A. (CH) | 2012-02-08 | — | — | EP | disclosed |