Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5350560 | 0.84 | KDM4E (0.44) | KDM4EPOLBGAAGFER | |
| SCHEMBL10518971 | 0.82 | CYP3A4 (0.41) | KDM4EPOLBGAAALDH1A1 | |
| SCHEMBL3125277 | 0.81 | KDM4E (0.53) | KDM4EPOLBGAAGFERALDH1A1 | |
| SCHEMBL3899027 | 0.79 | KDM4E (0.77) | KDM4EPOLBGAAALDH1A1HTT | |
| SCHEMBL2601960 | 0.79 | KDM4E (0.61) | KDM4EPOLBGAAALDH1A1LMNA | |
| SCHEMBL9999181 | 0.77 | HTT (0.41) | KDM4EGAAALDH1A1LMNAHTT | |
| SCHEMBL10629350 | 0.75 | KDM4E (0.56) | KDM4EGAAALDH1A1LMNA | |
| SCHEMBL10520470 | 0.74 | KDM4E (0.53) | KDM4EPOLBGAAALDH1A1LMNA | |
| SCHEMBL29918238 | 0.74 | KDM4E (0.53) | KDM4EPOLBGAAGFERALDH1A1 | |
| SCHEMBL3549850 | 0.74 | KDM4E (0.53) | KDM4EPOLBGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |