SCHEMBL5361541 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	AR	P10275	11/20	0.51

▸	EGLN2	Q96KS0	1/20	0.34

▸	LMNA	P02545	2/20	0.33

▸	ALDH1A1	P00352	1/20	0.33

▸	SLC34A1	Q06495	2/20	0.33

▸	TP53	P04637	2/20	0.33

▸	MAPT	P10636	1/20	0.33

▸	BRD4	O60885	1/20	0.33

▸	FNTA	P49354	2/20	0.32

▸	FNTB	P49356	2/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5370036	0.89	AR (0.49)	AREGLN2LMNAALDH1A1SLC34A1
SCHEMBL5359725	0.88	AR (0.48)	AREGLN2LMNAALDH1A1SLC34A1
SCHEMBL5381340	0.88	AR (0.48)	AREGLN2LMNAALDH1A1SLC34A1
SCHEMBL5377673	0.88	AR (0.48)	AREGLN2LMNAALDH1A1SLC34A1
SCHEMBL5362977	0.88	AR (0.48)	ARLMNAALDH1A1SLC34A1TP53
SCHEMBL5364246	0.86	AR (0.47)	AREGLN2LMNAALDH1A1SLC34A1
SCHEMBL5364243	0.86	AR (0.47)	AREGLN2LMNAALDH1A1SLC34A1
SCHEMBL5364006	0.81	AR (0.52)	AREGLN2SLC34A1BRD4FNTA
SCHEMBL5358998	0.78	AR (0.54)	AREGLN2BRD4FNTAFNTB
SCHEMBL5360480	0.78	AR (0.42)	AREGLN2LMNAALDH1A1SLC34A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007145349-A2	SUBSTITUTED PYRROLE DERIVATIVES	TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP)	2007-12-21	—	—	WO	disclosed