Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5370036 | 0.80 | AR (0.49) | ARBRD4FNTAFNTBSLC34A1 | |
| SCHEMBL5359896 | 0.79 | AR (0.43) | ARGRIA2GRIA4BRD4FNTA | |
| SCHEMBL5361541 | 0.78 | AR (0.51) | ARBRD4FNTAFNTBSLC34A1 | |
| SCHEMBL5362977 | 0.77 | AR (0.48) | ARFNTAFNTBSLC34A1ALDH1A1 | |
| SCHEMBL5381340 | 0.75 | AR (0.48) | ARBRD4FNTAFNTBSLC34A1 | |
| SCHEMBL5359725 | 0.75 | AR (0.48) | ARBRD4SLC34A1EGLN2ALDH1A1 | |
| SCHEMBL5377673 | 0.75 | AR (0.48) | ARBRD4FNTAFNTBSLC34A1 | |
| SCHEMBL5365950 | 0.74 | AR (0.44) | ARGRIA2GRIA4BRD4FNTA | |
| SCHEMBL5358998 | 0.74 | AR (0.54) | ARGRIA2GRIA4BRD4FNTA | |
| SCHEMBL5364246 | 0.73 | AR (0.47) | ARBRD4FNTAFNTBSLC34A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |