SCHEMBL536156

SCHEMBL536156

COc1ccc(/C=C/C(=O)OCCC(C)C)c(OC)c1OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
ABCG2 Q9UNQ0 1/20 0.56
CYP1A1 P04798 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2D6 P10635 2/20 0.50
CYP1B1 Q16678 2/20 0.50
TP53 P04637 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
AKR1B10 O60218 4/20 0.46
AKR1B1 P15121 4/20 0.46
CHRNA7 P36544 1/20 0.46
CYP3A4 P08684 1/20 0.46
NFE2L2 Q16236 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MAPT P10636 1/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536158 1.00 LMNA (0.57) LMNATDP1ABCG2CYP1A1CYP1A2
SCHEMBL1275710 0.92 LMNA (0.50) LMNATDP1ABCG2CYP1A1CYP1A2
SCHEMBL28460175 0.91 LMNA (0.49) LMNATDP1ABCG2CYP1A1CYP1A2
SCHEMBL27632834 0.87 LMNA (0.57) LMNATDP1ABCG2AKR1B10AKR1B1
SCHEMBL1878198 0.87 ABCG2 (0.58) LMNAABCG2CYP1A1CYP1A2CYP2D6
SCHEMBL1878197 0.87 ABCG2 (0.58) LMNAABCG2CYP1A1CYP1A2CYP2D6
SCHEMBL1879576 0.85 ABCG2 (0.59) LMNAABCG2CYP1A1CYP1A2CYP2D6
SCHEMBL1879574 0.85 ABCG2 (0.59) LMNAABCG2CYP1A1CYP1A2CYP2D6
SCHEMBL1880415 0.83 ABCG2 (0.57) LMNAABCG2CYP1A1CYP1A2CYP2D6
SCHEMBL1880416 0.83 ABCG2 (0.57) LMNAABCG2CYP1A1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197239-A1 ZINC OXIDE POWDER, LIQUID DISPERSION, COATING MATERIAL, AND COSMETIC SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2025-06-19 US disclosed
US-20240415758-A1 COSMETIC SHISEIDO COMPANY, LTD. (JP) 2024-12-19 US disclosed
EP-4474354-A1 ZINC OXIDE POWDER, LIQUID DISPERSION, COATING MATERIAL, AND COSMETIC Sumitomo Osaka Cement Co., Ltd. (JP) 2024-12-11 EP disclosed
CN-117979961-A Stabilized compositions 鲁米兰特私人有限公司 2024-05-03 CN disclosed
US-8962684-B2 Antioxidant composition SHISEIDO COMPANY, LTD. (JP) 2015-02-24 US disclosed
US-8735442-B2 Composition for alleviating ultraviolet radiation-induced damage SHISEIDO COMPANY, LTD. (JP) 2014-05-27 US disclosed
US-8637572-B2 Composition for promoting collagen production SHISEIDO COMPANY, LTD. (JP) 2014-01-28 US disclosed
EP-2516511-A2 THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT Dow Corning Toray Co., Ltd. (JP) 2012-10-31 EP disclosed
US-20120184620-A1 ANTIOXIDANT COMPOSITION SHISEIDO COMPANY, LTD. 2012-07-19 US disclosed
US-20120184619-A1 COMPOSITION FOR PROMOTING COLLAGEN PRODUCTION SHISEIDO COMPANY, LTD 2012-07-19 US disclosed
US-20120142941-A1 COMPOSITION FOR ALLEVIATING ULTRAVIOLET RADIATION-INDUCED DAMAGE SHISEIDO COMPANY, LTD. 2012-06-07 US disclosed
US-20120122951-A1 SKIN-WHITENING AGENT AND COSMETIC METHOD FOR WHITENING SKIN SHISEIDO COMPANY, LTD. 2012-05-17 US disclosed
EP-2415453-A1 SKIN-WHITENING AGENT AND COSMETIC METHOD FOR WHITENING SKIN Shiseido Company, Ltd. (JP) 2012-02-08 EP disclosed
WO-2011078395-A2 THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT DOW CORNING TORAY CO., LTD. (JP) 2011-06-30 WO disclosed
US-20090136540-A1 Anti-aging composition and collagen production promoting composition SHISEIDO COMPANY, LTD. 2009-05-28 US disclosed
US-20070134265-A1 Anti-aging composition and collagen production promoting composition SHISEIDO COMPANY, LTD. (JP) 2007-06-14 US disclosed