Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224049 | 0.91 | HSD17B10 (0.40) | HSD17B10SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL4871852 | 0.89 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL25930944 | 0.86 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2POLBEPHX2NR1H2 | |
| SCHEMBL18591178 | 0.86 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2POLBEPHX2NR1H2 | |
| SCHEMBL10215476 | 0.85 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL2126924 | 0.85 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL31148270 | 0.85 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL16824583 | 0.80 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2HSD11B1NPC1EPHX2 | |
| SCHEMBL30396554 | 0.80 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2HSD11B1NPC1EPHX2 | |
| SCHEMBL14488388 | 0.80 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2HSD11B1NPC1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814893-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006055070-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2006-05-26 | — | — | WO | disclosed |