Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20335022 | 0.83 | MEN1 (0.48) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL4814906 | 0.83 | MEN1 (0.48) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL30832481 | 0.83 | MEN1 (0.50) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL6515271 | 0.83 | MEN1 (0.50) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL4058433 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL839569 | 0.82 | MEN1 (0.47) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL29603146 | 0.82 | — | — | |
| SCHEMBL317040 | 0.82 | MEN1 (0.47) | MEN1KMT2ANPSR1 | |
| SCHEMBL630728 | 0.82 | MEN1 (0.47) | MEN1KMT2ANPSR1 | |
| SCHEMBL205894 | 0.82 | MEN1 (0.47) | MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414352-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010117704-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-14 | — | — | WO | disclosed |
| WO-2009073056-A1 | NOVEL TETRACYCLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2009-06-11 | — | — | WO | disclosed |