Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.57 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364332 | 0.93 | AR (0.58) | ARMAPK1KDM4ELMNAMAPT | |
| SCHEMBL5356694 | 0.92 | AR (0.57) | ARMAPK1KDM4ELMNAMAPT | |
| SCHEMBL5364810 | 0.89 | AR (0.59) | ARMAPK1KDM4ELMNAMAPT | |
| SCHEMBL5361382 | 0.86 | AR (0.48) | ARMAPK1KDM4ELMNAMAPT | |
| SCHEMBL6468898 | 0.75 | AR (0.64) | ARMAPK1KDM4ELMNAMAPT | |
| SCHEMBL14347629 | 0.75 | AR (0.43) | ARMAPK1KDM4EFNTAFNTB | |
| SCHEMBL6468911 | 0.73 | AR (1.00) | ARLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3086581 | 0.73 | MAPK1 (0.42) | ARMAPK1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14348316 | 0.73 | MAPT (0.46) | ARMAPK1KDM4ELMNAMAPT | |
| SCHEMBL14347708 | 0.71 | GRM2 (0.44) | MAPK1KDM4ELMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |