Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356694 | 0.93 | AR (0.57) | ARMAPK1KDM4ELMNAMAPT | |
| SCHEMBL5363522 | 0.93 | AR (0.57) | ARMAPK1KDM4ELMNAMAPT | |
| SCHEMBL5364810 | 0.91 | AR (0.59) | ARMAPK1KDM4ELMNAMAPT | |
| SCHEMBL5361382 | 0.80 | AR (0.48) | ARMAPK1KDM4ELMNAMAPT | |
| SCHEMBL6468898 | 0.77 | AR (0.64) | ARMAPK1KDM4ELMNAMAPT | |
| SCHEMBL6468911 | 0.75 | AR (1.00) | ARLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3081369 | 0.73 | MAPK1 (0.43) | ARMAPK1KDM4ELMNAMAPT | |
| SCHEMBL6469698 | 0.71 | AR (0.61) | ARKDM4ELMNAMAPTFNTA | |
| SCHEMBL6469303 | 0.71 | AR (0.67) | ARMAPT | |
| SCHEMBL5359751 | 0.69 | LMNA (0.52) | ARMAPK1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |