Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.74 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363610 | 1.00 | RXRA (0.74) | RXRARARARARBRARGRXRB | |
| SCHEMBL5368463 | 0.85 | RXRA (1.00) | RXRARARARARBRARGRXRB | |
| SCHEMBL5368456 | 0.85 | RXRA (1.00) | RXRARARARARBRARGRXRB | |
| SCHEMBL5361764 | 0.73 | RXRA (1.00) | RXRARARARARBRARGRXRB | |
| SCHEMBL5361755 | 0.73 | RXRA (1.00) | RXRARARARARBRARGRXRB | |
| SCHEMBL5371773 | 0.72 | RXRA (0.77) | RXRARARARARBRARGRXRB | |
| SCHEMBL5356964 | 0.68 | RXRA (1.00) | RXRARARARARBRARGRXRB | |
| SCHEMBL5356973 | 0.68 | RXRA (1.00) | RXRARARARARBRARGRXRB | |
| SCHEMBL13752411 | 0.67 | RXRA (0.72) | RXRARARARARBRARGRXRB | |
| SCHEMBL5356750 | 0.66 | RXRA (1.00) | RXRARARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173134-B2 | Selective RXR ligands | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-06 | — | — | US | claimed |