Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.59 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759150 | 0.84 | CACNA1B (0.49) | CACNA1BPTGESTAS2R14SMN1; SMN2ALDH1A1 | |
| SCHEMBL5759155 | 0.80 | CACNA1B (0.51) | CACNA1BPTGESTAS2R14SMN1; SMN2ALDH1A1 | |
| SCHEMBL5364313 | 0.74 | CACNA1B (1.00) | CACNA1BALDH1A1 | |
| SCHEMBL5343462 | 0.74 | CACNA1B (0.40) | CACNA1BSMN1; SMN2ALDH1A1HTTNPC1 | |
| SCHEMBL5364318 | 0.74 | CACNA1B (0.61) | CACNA1BPTGESTAS2R14SMN1; SMN2ALDH1A1 | |
| SCHEMBL5351860 | 0.70 | SMN1; SMN2 (0.51) | CACNA1BSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL5759147 | 0.70 | CACNA1B (0.52) | CACNA1BPTGESTAS2R14SMN1; SMN2ALDH1A1 | |
| SCHEMBL5356390 | 0.69 | CACNA1B (0.57) | CACNA1BPTGESTAS2R14SMN1; SMN2ALDH1A1 | |
| SCHEMBL28001541 | 0.68 | L3MBTL1 (0.45) | CACNA1BSMN1; SMN2ALDH1A1HTTNPC1 | |
| SCHEMBL20131479 | 0.68 | SMN1; SMN2 (0.59) | CACNA1BSMN1; SMN2ALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166590-B2 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-23 | — | — | US | disclosed |
| US-20030013725-A1 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | CACNA1B, SCN1A, SCN2A | CACNA1B 1/4885PTGES 358/4885TAS2R14 3964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.