Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 5/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27667528 | 0.77 | CTSS (0.48) | GRM5MGAT2ALOX5EPHX2CTSL | |
| SCHEMBL3012389 | 0.77 | CTSS (0.48) | GRM5MGAT2ALOX5EPHX2CTSL | |
| SCHEMBL5363803 | 0.72 | GRM5 (0.43) | GRM5 | |
| SCHEMBL5352211 | 0.70 | NOTUM (0.45) | MGAT2ALOX5EPHX2CTSLCTSS | |
| SCHEMBL5363794 | 0.69 | NOTUM (0.44) | MGAT2ALOX5EPHX2CTSLCTSS | |
| SCHEMBL24823574 | 0.67 | NOTUM (0.49) | MGAT2ALOX5EPHX2NOTUMKDM4A | |
| SCHEMBL12060492 | 0.67 | NOTUM (0.53) | MGAT2ALOX5EPHX2NOTUMKDM4A | |
| SCHEMBL4572948 | 0.67 | NOTUM (0.50) | ALOX5EPHX2CTSLCTSSCTSK | |
| SCHEMBL24495180 | 0.67 | HDAC1 (0.49) | ALOX5EPHX2NOTUMKDM4AKDM2B | |
| SCHEMBL29713576 | 0.67 | HDAC1 (0.49) | ALOX5EPHX2NOTUMKDM4AKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307095-B2 | Osteoporosis; antiarthritic agents; antidiabetic agents; antiinflammatory agents; Alzheimer's disease; shock; central nervous stsrem disorders; anticancer agents; multiple sclerosis, (S)-2-(Benzooxazol-2-ylamino)-3-cyclohexyl-N-[2-(5-fluoro-2,3-dihydro-indol-1-yl)-ethyl]-propionamide | IRM LLC (BM) | 2007-12-11 | — | — | US | disclosed |