Methacrylic Acid

Methacrylic Acid

SCHEMBL5364409

C=C(C)C(=O)O.CCCOC(=O)C(C)=C[Si](OC)(OC)OC

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
THRB P10828 1/20 0.37
HCAR2 Q8TDS4 1/20 0.34
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30018944 0.91 HCAR2 (0.36) TSHRTHRBHCAR2GAASMN1; SMN2
SCHEMBL146699 0.91 HCAR2 (0.36) TSHRTHRBHCAR2GAASMN1; SMN2
SCHEMBL28796433 0.90 TSHR (0.45) TSHRTHRBHCAR2GAASMN1; SMN2
SCHEMBL8067573 0.90 ALDH1A1 (0.44) TSHRTHRBHCAR2GAASMN1; SMN2
Hydrogen Sulfide SCHEMBL3135895 0.89 HCAR2 (0.35) TSHRTHRBHCAR2GAASMN1; SMN2
Ammonia Solution, Strong SCHEMBL28325492 0.89 HCAR2 (0.35) TSHRTHRBHCAR2GAASMN1; SMN2
SCHEMBL18495734 0.89 HCAR2 (0.35) TSHRTHRBHCAR2GAASMN1; SMN2
Hydrochloric Acid SCHEMBL28010821 0.87 HCAR2 (0.34) TSHRTHRBHCAR2GAASMN1; SMN2
SCHEMBL7147977 0.81 ALDH1A1 (0.47) TSHRHCAR2
Styrene SCHEMBL5361711 0.80 POLB (0.42) TSHRGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114846039-A Method for producing polyurethane composite material, and dental cutting material 德山齿科株式会社 2022-08-02 CN disclosed
US-7160953-B2 Polymeric surface coatings BIOCOMPATIBLES UK LIMITED (GB) 2007-01-09 US disclosed
US-20040176556-A1 Polymeric surface coatings BIOCOMPATIBLES LIMITED 2004-09-09 US disclosed