Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369888 | 0.85 | THRB (0.57) | THRBHDAC6HDAC1 | |
| SCHEMBL8228581 | 0.85 | THRB (0.59) | THRBHDAC6HDAC1 | |
| SCHEMBL8219821 | 0.84 | THRB (0.60) | THRBHDAC6HDAC1 | |
| SCHEMBL5364594 | 0.84 | THRB (0.49) | THRBHDAC6HDAC1KCNH2 | |
| SCHEMBL5354669 | 0.83 | THRB (0.58) | THRBMRGPRX4 | |
| SCHEMBL5374710 | 0.81 | THRB (0.60) | THRB | |
| SCHEMBL8226125 | 0.81 | THRB (0.65) | THRBHDAC6HDAC1 | |
| SCHEMBL8219823 | 0.81 | THRB (0.63) | THRBHDAC6HDAC1 | |
| SCHEMBL5324066 | 0.81 | THRB (0.61) | THRB | |
| SCHEMBL8228557 | 0.81 | THRB (0.58) | THRBHDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |