Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Benzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL11418994 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRFFAR3 | |
| Benzene SCHEMBL10534848 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRFFAR3 | |
| Benzene SCHEMBL406944 | 0.97 | ALDH1A1 (0.38) | ALDH1A1TSHRFFAR3 | |
| Alcohol SCHEMBL10600288 | 0.89 | — | — | |
| Alcohol SCHEMBL28056662 | 0.89 | — | — | |
| Alcohol SCHEMBL29125643 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TSHR | |
| Benzene SCHEMBL11413448 | 0.88 | ALDH1A1 (0.33) | ALDH1A1TSHRFFAR3 | |
| Benzene SCHEMBL483874 | 0.86 | — | — | |
| Benzene SCHEMBL21828967 | 0.86 | — | — | |
| Benzene SCHEMBL471859 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125953-A1 | COATED PARTICLES FOR TURF INFILL | COGNITION THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | claimed |
| WO-2022126013-A1 | COATED PARTICLES FOR TURF INFILL | PREFERRED TECHNOLOGY, LLC (US) | 2022-06-16 | — | — | WO | claimed |
| US-20220186037-A1 | COATED PARTICLES FOR TURF INFILL | PREFERRED TECHNOLOGY, LLC | 2022-06-16 | — | — | US | claimed |
| US-9382469-B2 | Process for the production of coated proppants | ASHLAND-SUDCHEMIE-KERNFEST GMBH (DE) | 2016-07-05 | — | — | US | claimed |
| US-20140345864-A1 | METHOD FOR PRODUCING COATED PROPPANTS | ASHLAND-SUDCHEMIE-KERNFEST GMBH (DE) | 2014-11-27 | — | — | US | claimed |
| US-20140060833-A1 | PROCESS FOR THE PRODUCTION OF COATED PROPPANTS | Ashland-Sudchemie-Kemfest GmbH (DE) | 2014-03-06 | — | — | US | claimed |
| US-20120279703-A1 | COATED AND CURED PROPPANTS | ALTER DOMUS (US) LLC, AS ADMINISTRATIVE AGENT | 2012-11-08 | — | — | US | claimed |
| US-20120283153-A1 | COATED AND CURED PROPPANTS | ALTER DOMUS (US) LLC, AS ADMINISTRATIVE AGENT | 2012-11-08 | — | — | US | claimed |
| US-20240228691-A1 | SUSTAINABLE RESILIENT PLANK | HMTX INDUSTRIES LLC | 2024-07-11 | — | — | US | disclosed |
| US-11958933-B2 | Sustainable resilient plank | TOWER IPCO COMPANY LIMITED (IE) | 2024-04-16 | — | — | US | disclosed |
| US-11760924-B2 | Proppant with enhanced interparticle bonding | PREFERRED TECHNOLOGY, LLC (US) | 2023-09-19 | — | — | US | disclosed |
| CN-115667343-A | Sustainable elastic plate | 塔伊普科有限公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2022126013-A1 | COATED PARTICLES FOR TURF INFILL | PREFERRED TECHNOLOGY, LLC (US) | 2022-06-16 | — | — | WO | disclosed |
| US-20220186037-A1 | COATED PARTICLES FOR TURF INFILL | PREFERRED TECHNOLOGY, LLC | 2022-06-16 | — | — | US | disclosed |
| US-20120279703-A1 | COATED AND CURED PROPPANTS | ALTER DOMUS (US) LLC, AS ADMINISTRATIVE AGENT | 2012-11-08 | — | — | US | disclosed |
| WO-2012151260-A1 | COATED AND CURED PROPPANTS | PREFERRED UNLIMITED, INC. (US) | 2012-11-08 | — | — | WO | disclosed |
| US-7262255-B2 | Polyesterether copolymer; neutralized with amine, ammonia | ASHLAND-SUDCHEMIE-KERNFEST GMBH (DE) | 2007-08-28 | — | — | US | disclosed |
| US-20040157986-A1 | Polyester resin emulsion and two-component aqueous paint | ASK CHEMICALS GMBH (DE) | 2004-08-12 | — | — | US | disclosed |
| US-4184031-A | Control of cure rate of polyurethane resins | THIOKOL CORPORATION (US) | 1980-01-15 | — | — | US | disclosed |
| US-4110135-A | CURED HYDROXY TERMINATED POLYBUTADIENE BASED POLYURETHANE BOUND GRAIN | THIOKOL CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |