Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 7/20 | 0.75 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.75 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.75 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.75 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.75 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.75 |
| ▸ | SRC | P12931 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.72 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.70 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.70 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.70 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.70 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.70 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.66 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.66 |
| ▸ | LDHA | P00338 | 1/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | FBP1 | P09467 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331755 | 1.00 | P2RY1 (0.75) | P2RY1P2RX3P2RX2P2RY2P2RX4 | |
| SCHEMBL29908846 | 1.00 | P2RY1 (0.75) | P2RY1P2RX3P2RX2P2RY2P2RX4 | |
| SCHEMBL163281 | 1.00 | P2RY1 (0.75) | P2RY1P2RX3P2RX2P2RY2P2RX4 | |
| SCHEMBL163282 | 1.00 | P2RY1 (0.75) | P2RY1P2RX3P2RX2P2RY2P2RX4 | |
| SCHEMBL1331745 | 1.00 | P2RY1 (0.75) | P2RY1P2RX3P2RX2P2RY2P2RX4 | |
| SCHEMBL27837591 | 0.99 | P2RY1 (0.74) | P2RY1P2RX3P2RX2P2RY2P2RX4 | |
| SCHEMBL28009685 | 0.99 | P2RY1 (0.74) | P2RY1P2RX3P2RX2P2RY2P2RX4 | |
| Pyrophosphoric Acid SCHEMBL27579246 | 0.99 | P2RY1 (0.74) | P2RY1P2RX3P2RX2P2RY2P2RX4 | |
| SCHEMBL29134096 | 0.99 | P2RY1 (0.74) | P2RY1P2RX3P2RX2P2RY2P2RX4 | |
| SCHEMBL23711717 | 0.99 | P2RX3 (0.74) | P2RY1P2RX3P2RX2P2RY2P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169900-B2 | Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy alkylene glycols | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20060111275-A1 | Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy alkylene glycols | ACHARYA SEETHARAMA A | 2006-05-25 | — | — | US | disclosed |
| US-7019117-B2 | Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy alkylene glycols | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2006-03-28 | — | — | US | disclosed |
| US-20040002443-A1 | Size enhanced hemoglobins: surface decoration and crosslinking of the protein with polyoxy alkylene glycols | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2004-01-01 | — | — | US | disclosed |
| WO-2003008932-A2 | SIZE ENHANCED HEMOGLOBINS: SURFACE DECORATION AND CROSSLINKING OF THE PROTEIN WITH POLYOXY AKYLENE GLYCOLS | ALBERT EINSTEIN COLLEGE OF MEDECINE OF YESHIVA UNIVERSITY (US) | 2003-01-30 | — | — | WO | disclosed |