Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138663 | 0.86 | SLC6A3 (0.52) | SLC6A3SLC6A2SLC6A4CYP2D6HTR2C | |
| SCHEMBL140633 | 0.72 | SLC6A3 (0.68) | SLC6A3SLC6A2SLC6A4CYP2D6HTR2C | |
| SCHEMBL6025372 | 0.72 | SLC6A2 (0.78) | SLC6A3SLC6A2SLC6A4CYP2D6HTR2C | |
| SCHEMBL10830185 | 0.70 | SLC6A3 (0.51) | SLC6A3SLC6A2SLC6A4HTR2CKDM4E | |
| SCHEMBL2722771 | 0.70 | SLC6A2 (0.55) | SLC6A3SLC6A2SLC6A4CYP2D6HTR2C | |
| SCHEMBL14338223 | 0.69 | SLC6A2 (0.50) | SLC6A3SLC6A2SLC6A4CYP2D6HTR2C | |
| SCHEMBL12702697 | 0.67 | SLC6A2 (0.62) | SLC6A3SLC6A2SLC6A4CYP2D6HTR2C | |
| SCHEMBL141728 | 0.66 | SLC6A2 (0.48) | SLC6A3SLC6A2SLC6A4CYP2D6HTR2C | |
| SCHEMBL11025430 | 0.66 | SLC6A2 (0.47) | SLC6A3SLC6A2SLC6A4CYP2D6HTR2C | |
| SCHEMBL12459423 | 0.65 | SLC6A2 (0.66) | SLC6A3SLC6A2SLC6A4CYP2D6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007041463-A2 | ELECTRICAL DEVICES AND ANTI-SCARRING DRUG COMBINATIONS | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |