Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | CCR1 | P32246 | 3/20 | 0.46 |
| ▸ | CCR5 | P51681 | 3/20 | 0.46 |
| ▸ | CCR8 | P51685 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28681737 | 0.98 | KDM4E (0.47) | KDM4ESMN1; SMN2LMNATP53CCR1 | |
| SCHEMBL31261515 | 0.95 | KDM4E (0.50) | KDM4ESMN1; SMN2LMNATP53CCR1 | |
| SCHEMBL1817511 | 0.95 | KDM4E (0.50) | KDM4ESMN1; SMN2LMNATP53CCR1 | |
| Hydrochloric Acid SCHEMBL28716572 | 0.93 | KDM4E (0.48) | KDM4ESMN1; SMN2LMNATP53CCR1 | |
| SCHEMBL12626761 | 0.93 | KDM4E (0.52) | KDM4ESMN1; SMN2LMNATP53CCR1 | |
| SCHEMBL27845489 | 0.90 | HTR2C (0.47) | KDM4ESMN1; SMN2LMNATP53CCR1 | |
| SCHEMBL28374091 | 0.87 | KDM4E (0.60) | KDM4ESMN1; SMN2LMNATP53CCR1 | |
| SCHEMBL31290750 | 0.83 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2LMNATP53CCR1 | |
| SCHEMBL6679713 | 0.83 | CCR1 (0.46) | KDM4ESMN1; SMN2LMNATP53CCR1 | |
| SCHEMBL27908766 | 0.82 | KDM4E (0.44) | KDM4ESMN1; SMN2LMNATP53CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9520570-B2 | Organic electronic device and method for the production thereof | OSRAM OLED GMBH (DE) | 2016-12-13 | — | — | US | disclosed |
| US-9520570-B2 | Organic electronic device and method for the production thereof | OSRAM OLED GMBH (DE) | 2016-12-13 | — | — | US | disclosed |
| EP-2483945-B1 | ORGANIC ELECTRONIC DEVICE AND METHOD FOR THE PRODUCTION THEREOF | OSRAM OLED GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| EP-2342772-B1 | ORGANIC ELECTRONIC COMPONENT AND METHOD FOR THE PRODUCTION THEREOF | OSRAM OLED GMBH (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-8558223-B2 | Organic electronic component and method for the production thereof | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2013-10-15 | — | — | US | disclosed |
| US-8558223-B2 | Organic electronic component and method for the production thereof | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2013-10-15 | — | — | US | disclosed |
| US-20120286253-A1 | Organic Electronic Device and Method for the Production Thereof | OSRAM OLED GMBH (DE) | 2012-11-15 | — | — | US | disclosed |
| US-20120286253-A1 | Organic Electronic Device and Method for the Production Thereof | OSRAM OLED GMBH (DE) | 2012-11-15 | — | — | US | disclosed |
| US-20110253991-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2011-10-20 | — | — | US | disclosed |
| US-20110253991-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2011-10-20 | — | — | US | disclosed |
| EP-2378584-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | Pioneer Corporation (JP) | 2011-10-19 | — | — | EP | disclosed |
| WO-2011039323-A2 | ORGANIC ELECTRONIC DEVICE AND METHOD FOR THE PRODUCTION THEREOF | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2011-04-07 | — | — | WO | disclosed |
| WO-2010034304-A2 | ORGANIC ELECTRONIC COMPONENT AND METHOD FOR THE PRODUCTION THEREOF | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |
| US-7271266-B2 | Substituted 2,3-diphenyl pyridines | MERCK & CO., INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-20050182103-A1 | Substituted 2,3-diphenyl pyridines | MERCK SHARP & DOHME CORP. | 2005-08-18 | — | — | US | disclosed |
| EP-1492784-A2 | SUBSTITUTED 2,3-DIPHENYL PYRIDINES | Merck & Co., Inc. (US) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082191-A2 | SUBSTITUTED 2,3-DIPHENYL PYRIDINES | MERCK & CO., INC. (US) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182103-A1 | Substituted 2,3-diphenyl pyridines | CNR1, CNR2, MAG | KDM4E 1804/4885SMN1; SMN2 874/4885LMNA 2024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.