Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 3/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349078 | 0.98 | MCHR1 (0.47) | MAPTKDM4EGFERMCHR1ALDH1A1 | |
| SCHEMBL5352801 | 0.95 | MCHR1 (0.47) | MAPTKDM4EGFERMCHR1ALDH1A1 | |
| SCHEMBL4816102 | 0.92 | POLB (0.43) | MAPTKDM4EGFERMCHR1ALDH1A1 | |
| SCHEMBL4817686 | 0.80 | DHODH (0.53) | MAPTKDM4EGFERALDH1A1NPC1 | |
| SCHEMBL17786499 | 0.71 | KDM4E (0.64) | MAPTKDM4EGFERALDH1A1NPC1 | |
| SCHEMBL28476846 | 0.70 | PLAU (0.52) | MAPTKDM4EALDH1A1SMN1; SMN2ACHE | |
| SCHEMBL24165902 | 0.69 | BACE1 (0.42) | MAPTKDM4EGFERNPC1RAB9A | |
| SCHEMBL24165808 | 0.69 | BACE1 (0.42) | MAPTKDM4EGFERNPC1RAB9A | |
| SCHEMBL24165924 | 0.69 | BACE1 (0.42) | MAPTKDM4EGFERNPC1RAB9A | |
| SCHEMBL24165807 | 0.69 | BACE1 (0.42) | MAPTKDM4EGFERNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189714-B2 | N-type calcium channel antagonists for the treatment of pain | ASTRAZENECA AB (SE) | 2007-03-13 | — | — | US | disclosed |