Glycerin

Glycerin

SCHEMBL5366679

CCCCCCCCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCCCCCCCC.OCC(O)CO

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.69
KDM4E B2RXH2 1/20 0.69
DUSP3 P51452 1/20 0.69
MEN1 O00255 1/20 0.69
KMT2A Q03164 1/20 0.69
MAPT P10636 2/20 0.59
MAPK1 P28482 1/20 0.59
DGKA P23743 2/20 0.58
PRKCA P17252 3/20 0.51
PRKCE Q02156 1/20 0.51
PRKCQ Q04759 1/20 0.51
PRKCD Q05655 1/20 0.51
ENPP2 Q13822 3/20 0.48
TRPV1 Q8NER1 1/20 0.48
FAAH O00519 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL10318794 1.00 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
Glycerin SCHEMBL29035507 1.00 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
Glycerin SCHEMBL5443125 1.00 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
Glycerin SCHEMBL27984269 1.00 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
Glycerin SCHEMBL28511354 1.00 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
Glycerin SCHEMBL6736626 1.00 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
Glycerin SCHEMBL7739443 1.00 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
Glycerin SCHEMBL28060827 1.00 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
Glycerin SCHEMBL28510773 1.00 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A
Glycerin SCHEMBL10319222 1.00 LMNA (0.69) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105461693-B CRTH2 agonist compounds and application thereof 广东东阳光药业有限公司 2019-10-25 CN disclosed
CN-105764900-B CRTH2 agonist compounds and application thereof 广东东阳光药业有限公司 2018-04-03 CN disclosed
CN-105764900-A Compounds as CRTH2 antagonist and uses thereof 广东东阳光药业有限公司 2016-07-13 CN disclosed
CN-105524053-A Benzothiophene tetrahydride compound GUANGDONG HEC PHARMACEUTICAL 2016-04-27 CN disclosed
EP-3002004-A1 TOPICAL SKIN CARE COMPOSITION Galderma S.A. (CH) 2016-04-06 EP disclosed
CN-105461693-A Crth2 antagonist compound and use thereof GUANGDONG HEC PHARMACEUTICAL 2016-04-06 CN disclosed
EP-1562531-B1 TOPICAL SKIN CARE COMPOSITION GALDERMA SA (CH) 2016-01-13 EP disclosed
US-7169401-B2 Topical skin care composition containing refined peanut oil HILL DERMACEUTICALS, INC. (US) 2007-01-30 US disclosed
EP-1696868-A1 TOPICAL SKIN CARE COMPOSITION CONTAINING REFINED PEANUT OIL Hill Dermaceuticals, Inc. (US) 2006-09-06 EP disclosed
US-20050053635-A1 Topical skin care composition containing refined peanut oil HILL DERMACEUTICALS, INC. 2005-03-10 US disclosed
WO-2005009406-A1 TOPICAL SKIN CARE COMPOSITION CONTAINING REFINED PEANUT OIL HILL DERMACEUTICALS, INC. (US) 2005-02-03 WO disclosed
EP-0751928-A1 DL- DI- OR TRI-HYDROXYPHENYLGLYCINE ALKYL ESTERS FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC CONDITIONS Ciba SC Holding AG (CH) 1997-01-08 EP disclosed
WO-1995025715-A1 DL- DI- OR TRI-HYDROXYPHENYLGLYCINE ALKYL ESTERS FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC CONDITIONS CIBA-GEIGY AG (CH) 1995-09-28 WO disclosed