Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.73 |
| ▸ | FDPS | P14324 | 2/20 | 0.70 |
| ▸ | BACE1 | P56817 | 2/20 | 0.62 |
| ▸ | TTR | P02766 | 2/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 4/20 | 0.57 |
| ▸ | BCHE | P06276 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353419 | 1.00 | MAOB (0.73) | MAOBFDPSBACE1TTRDPP4 | |
| SCHEMBL30594189 | 0.89 | FDPS (0.70) | MAOBFDPSTTRDPP4CYP3A4 | |
| SCHEMBL3678457 | 0.89 | FDPS (0.70) | MAOBFDPSTTRDPP4CYP3A4 | |
| SCHEMBL3678458 | 0.89 | FDPS (0.70) | MAOBFDPSTTRDPP4CYP3A4 | |
| SCHEMBL31087309 | 0.87 | FDPS (0.84) | MAOBFDPSTTRDPP4ACHE | |
| SCHEMBL8046247 | 0.87 | FDPS (0.84) | MAOBFDPSTTRDPP4ACHE | |
| SCHEMBL28859350 | 0.87 | FDPS (0.84) | MAOBFDPSTTRDPP4ACHE | |
| SCHEMBL28859349 | 0.87 | FDPS (0.84) | MAOBFDPSTTRDPP4ACHE | |
| SCHEMBL8046251 | 0.87 | FDPS (0.84) | MAOBFDPSTTRDPP4ACHE | |
| SCHEMBL30740002 | 0.86 | MAOB (0.77) | MAOBFDPSTTRDPP4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139414-A1 | NOVEL BENZYLIDENEACETONE DERIVATIVE AND USE THEREOF | KORPHARM CO., LTD. (KR) | 2021-05-13 | — | — | US | disclosed |
| EP-2697204-B1 | FLUORINATION OF ORGANIC COMPOUNDS | HARVARD COLLEGE (US) | 2017-03-08 | — | — | EP | disclosed |
| US-9150516-B2 | Fluorination of organic compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-06 | — | — | US | disclosed |
| US-20120316341-A1 | FLUORINATION OF ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-12-13 | — | — | US | disclosed |
| WO-2012142162-A2 | FLUORINATION OF ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-10-18 | — | — | WO | disclosed |
| US-7217723-B2 | Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. | EISAI CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-20050227959-A1 | Heterocyclic compound having oxime group | EISAI CO., LTD. (JP) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139414-A1 | NOVEL BENZYLIDENEACETONE DERIVATIVE AND USE THEREOF | EBP, CREBBP, BPTF | MAOB 2043/4885FDPS 2944/4885BACE1 840/4885 |
| US-20120316341-A1 | FLUORINATION OF ORGANIC COMPOUNDS | SLCO1B3, SLCO2B1, FLI1 | MAOB 155/4885FDPS 38/4885BACE1 2703/4885 |
| US-20050227959-A1 | Heterocyclic compound having oxime group | STAT6, HRH4, HRH2 | MAOB 913/4885FDPS 3297/4885BACE1 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.