Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 7/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14425369 | 1.00 | ENPP2 (0.46) | ENPP2HTR2AABATSIGMAR1PTPN7 | |
| SCHEMBL14425368 | 0.90 | ENPP2 (0.49) | ENPP2HTR2AABATSIGMAR1F2 | |
| SCHEMBL5359620 | 0.90 | ENPP2 (0.49) | ENPP2HTR2AABATSIGMAR1F2 | |
| SCHEMBL5368400 | 0.88 | ENPP2 (0.47) | ENPP2HTR2AABATSIGMAR1F2 | |
| SCHEMBL14425314 | 0.86 | F2 (0.48) | ENPP2SIGMAR1F2PLGPRSS1 | |
| SCHEMBL5362085 | 0.86 | F2 (0.48) | ENPP2SIGMAR1F2PLGPRSS1 | |
| SCHEMBL14425445 | 0.86 | F2 (0.48) | ENPP2SIGMAR1F2PLGPRSS1 | |
| SCHEMBL5374371 | 0.85 | ENPP2 (0.47) | ENPP2HTR2AABATSIGMAR1F2 | |
| SCHEMBL14425378 | 0.85 | ENPP2 (0.47) | ENPP2HTR2AABATSIGMAR1F2 | |
| SCHEMBL5364450 | 0.84 | GRIN2B (0.48) | ENPP2HTR2AABATSIGMAR1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259157-B2 | N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists | MERCK & CO., INC. (US) | 2007-08-21 | — | — | US | disclosed |