Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367301 | 1.00 | HTR2A (0.36) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| Fumaric Acid SCHEMBL29945132 | 0.76 | HTR2A (0.48) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| Fumaric Acid SCHEMBL11256018 | 0.76 | HTR2A (0.48) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| Fumaric Acid SCHEMBL5367297 | 0.76 | HTR2A (0.48) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| SCHEMBL11102660 | 0.73 | NPSR1 (0.33) | — | |
| SCHEMBL5365272 | 0.70 | HTR2A (0.59) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| Fumaric Acid SCHEMBL11248605 | 0.67 | HTR2A (0.45) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| Fumaric Acid SCHEMBL11248576 | 0.67 | HTR2A (0.45) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| SCHEMBL8413244 | 0.66 | HTR2B (0.56) | HTR2AHTR2CHTR7HTR2B | |
| SCHEMBL4667774 | 0.65 | HSD17B10 (0.52) | HTR2AHRH1HTR2CHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196193-B2 | Method for preparing 6-aminomethyl-6, 11-dihydro-5h-dibenz[b,e]azepine | KONICA MINOLTA CHEMICAL CO., LTD. (JP) | 2007-03-27 | — | — | US | disclosed |
| EP-1496051-B1 | METHOD FOR PREPARING 6-AMINOMETHYL-6,11-DIHYDRO-5H-DIBENZ(B,E)AZEPINE | KONICA MINOLTA CHEMICAL CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-20050209215-A1 | Method for preparing 6-aminomethyl-6,11-dihydro-5h-dibenz[b,e]azepine | KONICA MINOLTA CHEMICAL CO., LTD. (JP) | 2005-09-22 | — | — | US | disclosed |
| EP-1496051-A1 | METHOD FOR PREPARING 6-AMINOMETHYL-6,11-DIHYDRO-5H-DIBENZ(B,E)AZEPINE | Konica Minolta Chemical Co., Ltd. (JP) | 2005-01-12 | — | — | EP | disclosed |
| EP-0035749-B1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | C.H. BOEHRINGER SOHN (DE) | 1984-06-06 | — | — | EP | disclosed |
| EP-0035749-A1 | Heterocyclic compounds, their preparation and pharmaceutical compositions containing them | C.H. BOEHRINGER SOHN (DE) | 1981-09-16 | — | — | EP | disclosed |