Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935069 | 1.00 | REN (1.00) | RENCYP3A4 | |
| SCHEMBL2932249 | 0.93 | REN (1.00) | RENCYP3A4 | |
| SCHEMBL2932248 | 0.93 | REN (1.00) | RENCYP3A4 | |
| SCHEMBL2933944 | 0.93 | REN (1.00) | RENCYP3A4 | |
| SCHEMBL2933946 | 0.93 | REN (1.00) | RENCYP3A4 | |
| SCHEMBL5493803 | 0.88 | REN (1.00) | RENCYP3A4 | |
| SCHEMBL2935580 | 0.88 | REN (1.00) | RENCYP3A4 | |
| SCHEMBL2937601 | 0.86 | REN (1.00) | RENCYP3A4 | |
| SCHEMBL8263648 | 0.86 | REN (1.00) | RENCYP3A4 | |
| SCHEMBL2935049 | 0.86 | REN (0.79) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836163-A2 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | Novartis AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006066896-A2 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | NOVARTIS AG (CH) | 2006-06-29 | — | — | WO | disclosed |