SCHEMBL5367688

SCHEMBL5367688

CCCO[Si](CC(CC)OCC1CO1)(OCCC)OCCC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 3/20 0.37
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5367844 0.91 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL231866 0.87 ALDH1A1 (0.34) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL188276 0.83 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL231272 0.82 ALDH1A1 (0.35) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL5367540 0.81 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL17559511 0.81 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL5606138 0.78 ALDH1A1 (0.34) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL27850035 0.76 SMN1; SMN2 (0.33) SMN1; SMN2ALDH1A1TDP1
SCHEMBL28448623 0.76 ALDH1A1 (0.35) SMN1; SMN2ALDH1A1TDP1
SCHEMBL5606106 0.76 ALDH1A1 (0.35) SMN1; SMN2ALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106685-A Coating composition, method of making the same, and articles 广东华润涂料有限公司 2022-03-01 CN disclosed
CN-109196389-B Optical article comprising a substrate with an antireflection coating 蒙特利尔综合理工学院公司 2021-04-30 CN disclosed
EP-1764398-B1 Hard coat composiiton and optical element ITOH OPTICAL IND (JP) 2015-07-22 EP disclosed
US-20070251448-A1 Application method, applicator, optical member, and optical device SAKURADA KAZUAKI 2007-11-01 US disclosed
US-7250190-B2 Application method, applicator, optical member, and optical device SEIKO EPSON CORPORATION (JP) 2007-07-31 US disclosed
EP-1764398-A1 Hard coat composiiton and optical element Itoh Optical Industrial Co., Ltd. (JP) 2007-03-21 EP disclosed
EP-1273639-B1 OPTICAL ELEMENT ITOH OPTICAL IND (JP) 2006-10-25 EP disclosed
US-6773465-B1 Optical element ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 2004-08-10 US disclosed
US-20040142105-A1 Application method, applicator, optical member, and optical device SEIKO EPSON CORPORATION (JP) 2004-07-22 US disclosed
EP-1273639-A1 OPTICAL ELEMENT Itoh Optical Industrial Co., Ltd. (JP) 2003-01-08 EP disclosed
EP-0526975-B1 Coating composition for optical plastic moldings ITOH OPTICAL IND (JP) 1995-07-26 EP disclosed
US-5322888-A Curable mixture of hydrolyzable silicate, epoxy-containing silane, dicarboxylic acid or anhydride, and imidazole catalyst; protective coating for optical substrate having a high refractive index; radiation resistance ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 1994-06-21 US disclosed
EP-0526975-A2 Coating composition for optical plastic moldings ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 1993-02-10 EP disclosed
US-4294950-A POLYVALENT CARBOXYLIC ACID BONDED THERETO ITO OPTICAL INDUSTRIAL CO., LTD. (JP) 1981-10-13 US disclosed