Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 18/20 | 0.68 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.59 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4454325 | 0.91 | PTGER4 (0.65) | PTGER4PTGER2 | |
| SCHEMBL5362403 | 0.90 | PTGER4 (0.68) | PTGER4PTGER2SCN9A | |
| SCHEMBL4456286 | 0.89 | PTGER4 (0.67) | PTGER4PTGER2SCN9A | |
| SCHEMBL1285388 | 0.89 | PTGER4 (0.86) | PTGER4PTGER2 | |
| SCHEMBL19714369 | 0.89 | PTGER4 (0.86) | PTGER4PTGER2 | |
| SCHEMBL5365775 | 0.88 | PTGER4 (0.65) | PTGER4PTGER2SCN9A | |
| SCHEMBL5364451 | 0.88 | PTGER4 (0.65) | PTGER4PTGER2SCN9A | |
| SCHEMBL4453116 | 0.87 | PTGER4 (0.64) | PTGER4PTGER2SCN9A | |
| SCHEMBL4454925 | 0.87 | PTGER4 (0.78) | PTGER4PTGER2 | |
| SCHEMBL691924 | 0.86 | PTGER4 (0.76) | PTGER4PTGER2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663979-B1 | PHENYL OR PYRIDYL AMIDE COMPOUNDS AS PROSTAGLANDIN E2 ANTAGONISTS | RAQUALIA PHARMA INC (JP) | 2013-10-09 | — | — | EP | disclosed |
| US-7238714-B2 | Aryl or heteroaryl amide compounds | PFIZER JAPAN, INC. (JP) | 2007-07-03 | — | — | US | disclosed |
| US-20050065188-A1 | Aryl or heteroaryl amide compounds | ASKAT INC. (JP) | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065188-A1 | Aryl or heteroaryl amide compounds | HRH2, PTGER1, LTB4R2 | PTGER4 13/4885PTGER2 11/4885SCN9A 2703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.