Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18941357 | 0.74 | NPSR1 (0.38) | NPSR1L3MBTL1ATMTDP1ADORA3 | |
| SCHEMBL803116 | 0.74 | NPSR1 (0.41) | NPSR1L3MBTL1ATMTDP1ADORA3 | |
| SCHEMBL31059170 | 0.74 | NPSR1 (0.41) | NPSR1L3MBTL1ATMTDP1ADORA3 | |
| SCHEMBL536795 | 0.73 | NEK2 (0.43) | NPSR1L3MBTL1ATMTDP1ADORA3 | |
| SCHEMBL8715386 | 0.72 | NEK2 (0.42) | NPSR1L3MBTL1ATMTDP1ADORA3 | |
| SCHEMBL8064272 | 0.70 | NPSR1 (0.36) | NPSR1L3MBTL1ATMTDP1ADORA3 | |
| SCHEMBL18941371 | 0.64 | ADORA1 (0.40) | NPSR1L3MBTL1ATMTDP1ADORA3 | |
| SCHEMBL29552357 | 0.63 | ADORA1 (0.41) | NPSR1L3MBTL1ATMTDP1ADORA3 | |
| SCHEMBL20394079 | 0.63 | ADORA1 (0.41) | NPSR1L3MBTL1ATMTDP1ADORA3 | |
| SCHEMBL28928358 | 0.61 | ADORA1 (0.41) | NPSR1L3MBTL1ATMTDP1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675123-B1 | Cyclopropane derivatives and method of preparing the same | AJINOMOTO KK (JP) | 2001-02-21 | — | — | EP | claimed |
| US-5925756-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., INC. (JP) | 1999-07-20 | — | — | US | claimed |
| EP-0675123-A1 | Cyclopropane derivatives and method of preparing the same | Ajinomoto Co., Inc. (JP) | 1995-10-04 | — | — | EP | claimed |
| EP-2415777-B1 | PROCESS FOR PRODUCING NUCLEOSIDE | TAKEDA PHARMACEUTICAL (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-8653254-B2 | Process for producing nucleoside | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-02-18 | — | — | US | disclosed |
| US-20120071646-A1 | PROCESS FOR PRODUCING NUCLEOSIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
| EP-2415777-A1 | PROCESS FOR PRODUCING NUCLEOSIDE | Takeda Pharmaceutical Company Limited (JP) | 2012-02-08 | — | — | EP | disclosed |
| EP-0675123-B1 | Cyclopropane derivatives and method of preparing the same | AJINOMOTO KK (JP) | 2001-02-21 | — | — | EP | disclosed |
| US-5925756-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., INC. (JP) | 1999-07-20 | — | — | US | disclosed |
| US-5808134-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5777116-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., INC. (JP) | 1998-07-07 | — | — | US | disclosed |
| EP-0675123-A1 | Cyclopropane derivatives and method of preparing the same | Ajinomoto Co., Inc. (JP) | 1995-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071646-A1 | PROCESS FOR PRODUCING NUCLEOSIDE | NUDT1, PNP, HPRT1 | NPSR1 752/4885L3MBTL1 3853/4885ATM 4367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.