Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13082197 | 1.00 | HRH1 (0.62) | HRH1TBXAS1TDP1L3MBTL1CYP2A6 | |
| SCHEMBL5376031 | 0.98 | TDP1 (0.61) | HRH1TBXAS1TDP1L3MBTL1CYP2A6 | |
| SCHEMBL29438514 | 0.93 | CYP2A6 (0.59) | HRH1TBXAS1TDP1L3MBTL1CYP2A6 | |
| SCHEMBL702110 | 0.93 | CYP2A6 (0.59) | HRH1TBXAS1TDP1L3MBTL1CYP2A6 | |
| SCHEMBL348856 | 0.85 | CHRNA7 (0.57) | HRH1TBXAS1TDP1L3MBTL1CYP2A6 | |
| SCHEMBL29485667 | 0.85 | HRH1 (0.81) | HRH1TBXAS1TDP1L3MBTL1CYP2A6 | |
| SCHEMBL29485634 | 0.85 | HRH1 (0.81) | HRH1TBXAS1TDP1L3MBTL1CYP2A6 | |
| SCHEMBL3048356 | 0.85 | HRH1 (0.81) | HRH1TBXAS1TDP1L3MBTL1CYP2A6 | |
| SCHEMBL2845851 | 0.85 | HRH1 (0.81) | HRH1TBXAS1TDP1L3MBTL1CYP2A6 | |
| SCHEMBL8658187 | 0.85 | HRH1 (0.81) | HRH1TBXAS1TDP1L3MBTL1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253169-B2 | Aza compounds, pharmaceutical compositions and methods of use | GLIAMED, INC. (US) | 2007-08-07 | — | — | US | disclosed |