SCHEMBL5368339

SCHEMBL5368339

O=Cc1sccc1C=CF

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225281 0.80
SCHEMBL18826036 0.79 CYP2A6 (0.33) CYP2A6
SCHEMBL18826037 0.79 CYP2A6 (0.33) CYP2A6
SCHEMBL2720004 0.74
SCHEMBL18002834 0.72 NQO2 (0.45)
SCHEMBL1475043 0.69
SCHEMBL9696347 0.67 PRKDC (0.41) CYP2A6
SCHEMBL31337706 0.67 CYP2A6 (0.37) CYP2A6
SCHEMBL15630816 0.67 ALDH1A1 (0.43)
SCHEMBL11350874 0.66 CYP2A6 (0.33) CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007021693-A2 TRANSITION METAL CATALYZED CROSS-COUPLING OF 1-HALO-1-HALOALKENE COMPOUNDS REPLIDYNE, INC. (US) 2007-02-22 WO disclosed