⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694545 | 0.74 | — | — | |
| SCHEMBL18128104 | 0.70 | — | — | |
| Carbamic Acid SCHEMBL28072716 | 0.70 | — | — | |
| SCHEMBL5999710 | 0.67 | — | — | |
| Sulfur Dioxide SCHEMBL28204249 | 0.65 | — | — | |
| Sulfur Dioxide SCHEMBL9456700 | 0.65 | — | — | |
| Carbamic Acid SCHEMBL18703469 | 0.64 | — | — | |
| Urea SCHEMBL9702596 | 0.63 | — | — | |
| Thiourea SCHEMBL7036296 | 0.60 | — | — | |
| SCHEMBL31058189 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561054-A | Compounds and methods for treating alcohol use disorders | 索菲洛许奈制药有限公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-3743073-A1 | COMBINATION TREATMENTS FOR OPIOID CRISIS | Presti, Michael (US) | 2020-12-02 | — | — | EP | disclosed |
| WO-2019147606-A1 | COMBINATION TREATMENTS FOR OPIOID CRISIS | PRESTI MICHAEL (US) | 2019-08-01 | — | — | WO | disclosed |
| US-9504660-B2 | Retinaldehyde mimetics and inhibitors of retinaldehyde dehydrogenase I in the treatment of disorders | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20140378530-A1 | RETINALDEHYDE MIMETICS AND INHIBITORS OF RETINALDEHYDE DEHYDROGENASE I IN THE TREATMENT OF DISORDERS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2014-12-25 | — | — | US | disclosed |
| EP-2809309-A1 | RETINALDEHYDE MIMETICS AND INHIBITORS OF RETINALDEHYDE DEHYDROGENASE I IN THE TREATMENT OF DISORDERS | The Brigham and Women's Hospital, Inc. (US) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013116721-A1 | RETINALDEHYDE MIMETICS AND INHIBITORS OF RETINALDEHYDE DEHYDROGENASE I IN THE TREATMENT OF DISORDERS | THE BRIGHAM AND WOMEN'S HOSPTIAL, INC. (US) | 2013-08-08 | — | — | WO | disclosed |
| US-7250401-B2 | Therapeutic compositions | ADVANCED THERAPEUTICS AND DIAGNOSTICS, LC (US) | 2007-07-31 | — | — | US | disclosed |
| US-20050130904-A1 | Therapeutic compositions | THIOPHARMA, INC. | 2005-06-16 | — | — | US | disclosed |
| EP-1216703-B1 | Thiocarbamate sulfoxide composition for deterring ethanol ingestion | FAIMAN MORRIS D (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2003053337-A2 | THERAPEUTIC COMPOSITIONS | ADVANCED THERAPEUTICS & DIAGNOSTICS, LC (US) | 2003-07-03 | — | — | WO | disclosed |
| EP-1216703-A3 | Thiocarbamate sulfoxide composition for deterring ethanol ingestion | Faiman, Morris D. (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1216703-A2 | Thiocarbamate sulfoxide composition for deterring ethanol ingestion | Faiman, Morris D. (US) | 2002-06-26 | — | — | EP | disclosed |
| EP-0136016-A2 | N-(Substituted)-5-(substituted phenyl)-1,3-Oxazolidines: Herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1985-04-03 | — | — | EP | disclosed |
| US-4488897-A | Dichloromethyl oxadiazole herbicide antidotes | STAUFFER CHEMICAL COMPANY (US) | 1984-12-18 | — | — | US | disclosed |
| US-4314841-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1982-02-09 | — | — | US | disclosed |