SCHEMBL536873

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2602795	0.91	CYP1A2 (0.47)	CYP1A2NPSR1CYP2D6PKMSMN1; SMN2
	SCHEMBL27532767	0.83	BRD4 (0.43)	CYP1A2PRKCAPRKCDNPSR1CYP2D6
	SCHEMBL27388380	0.83	BRD4 (0.43)	CYP1A2PRKCAPRKCDNPSR1CYP2D6
	SCHEMBL2705027	0.83	CYP1A2 (0.56)	CYP1A2PRKCAPRKCDNPSR1CYP2D6
	SCHEMBL2705028	0.83	CYP1A2 (0.56)	CYP1A2PRKCAPRKCDNPSR1CYP2D6
	SCHEMBL8103307	0.83	CYP1A2 (0.56)	CYP1A2PRKCAPRKCDNPSR1CYP2D6
	SCHEMBL8193963	0.82	PRKCA (0.50)	PRKCAPRKCDNPSR1SMN1; SMN2MEN1
	SCHEMBL8193959	0.82	PRKCA (0.50)	PRKCAPRKCDNPSR1SMN1; SMN2MEN1
	SCHEMBL27900437	0.79	CYP1A2 (0.46)	CYP1A2NPSR1CYP2D6ALOX5ALDH1A1
	Carbamic Acid SCHEMBL8934351	0.79	CYP1A2 (0.60)	CYP1A2PRKCAPRKCDNPSR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.