SCHEMBL536946

SCHEMBL536946

CC(=O)C/C=C/C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536947 1.00
Acetone SCHEMBL5512169 0.97 TSHR (0.46)
SCHEMBL11918301 0.80
SCHEMBL10501974 0.80
SCHEMBL11044549 0.79
SCHEMBL1480896 0.79
SCHEMBL11044553 0.79
SCHEMBL18868445 0.78 ALDH1A1 (0.47)
SCHEMBL12572575 0.78 ALDH1A1 (0.47)
Glutaconate SCHEMBL2514167 0.77 ALDH1A1 (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2413973-A1 POLYMERIC CONJUGATES OF PACLITAXEL AND DOCETAXEL WITH PH-CONTROLLED RELEASING OF THE CANCEROSTATIC AGENT Zentiva, K.S. (CZ) 2012-02-08 EP claimed
WO-2010091650-A1 POLYMERIC CONJUGATES OF PACLITAXEL AND DOCETAXEL WITH PH-CONTROLLED RELEASING OF THE CANCEROSTATIC AGENT ZENTIVA, K.S. (CZ) 2010-08-19 WO claimed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
US-20180142121-A1 RESIN, COMPOSITION AND USE COVESTRO (NETHERLANDS) B.V. (NL) 2018-05-24 US disclosed
US-9902870-B2 Resin, composition and use DSM IP ASSETS B.V. (NL) 2018-02-27 US disclosed
US-9676889-B2 Polymer, process and composition DSM IP ASSETS B.V. (NL) 2017-06-13 US disclosed
US-20150111051-A1 RESIN, COMPOSITION AND USE COVESTRO (NETHERLANDS) B.V. (NL) 2015-04-23 US disclosed
US-20150024227-A1 BLOCK COPOLYMER, PROCESS AND COMPOSITION DSM IP ASSETS B.V. (NL) 2015-01-22 US disclosed
US-20150024217-A1 POLYMER, PROCESS AND COMPOSITION COVESTRO (NETHERLANDS) B.V. (NL) 2015-01-22 US disclosed
EP-2413973-A1 POLYMERIC CONJUGATES OF PACLITAXEL AND DOCETAXEL WITH PH-CONTROLLED RELEASING OF THE CANCEROSTATIC AGENT Zentiva, K.S. (CZ) 2012-02-08 EP disclosed
WO-2010091650-A1 POLYMERIC CONJUGATES OF PACLITAXEL AND DOCETAXEL WITH PH-CONTROLLED RELEASING OF THE CANCEROSTATIC AGENT ZENTIVA, K.S. (CZ) 2010-08-19 WO disclosed