Benzoguanamine

Benzoguanamine

SCHEMBL5369528

C=CC.COCCO.Nc1nc(N)nc(-c2ccccc2)n1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 3/20 0.53
ADORA1 P30542 3/20 0.53
ADORA3 P0DMS8 2/20 0.53
ADORA2B P29275 2/20 0.53
POLB P06746 1/20 0.53
DHPS P49366 6/20 0.45
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
NPSR1 Q6W5P4 1/20 0.40
HRH4 Q9H3N8 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
RAB9A P51151 1/20 0.39
IKBKB O14920 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoguanamine SCHEMBL4364795 0.82 ADORA2A (0.68) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL17477302 0.77 ADORA2A (0.76) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL3627859 0.77 ADORA2A (0.83) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL5369531 0.75 ADORA2A (0.58) ADORA2AADORA1ADORA3ADORA2BPOLB
Phenoxyethanol SCHEMBL4931324 0.74 ALDH1A1 (0.66) ALDH1A1CYP1A2CYP2C9HPGDCYP2C19
Anthracene SCHEMBL8837602 0.74 ALDH1A1 (0.39) ALOX15TSHRNPSR1ALDH1A1CYP1A2
Toluene SCHEMBL926846 0.74 TSHR (0.41) POLBTSHRNPSR1ALDH1A1HPGD
Benzoguanamine SCHEMBL27898 0.73 ADORA2A (1.00) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL28634836 0.73 ADORA2A (1.00) ADORA2AADORA1ADORA3ADORA2BPOLB
Benzoguanamine SCHEMBL917182 0.73 ADORA2A (1.00) ADORA2AADORA1ADORA3ADORA2BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7179399-B2 Material for forming protective film TOKYO OHKA KOGYO CO., LTD. (JP) 2007-02-20 US disclosed
US-20020182360-A1 Material for forming protective film TOKYO OHKA KOGYO CO., LTD. (JP) 2002-12-05 US disclosed