SCHEMBL5369542

SCHEMBL5369542

COC(=O)c1cc(OC)c2oc(NCc3cccc(Cl)c3)nc2c1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5372654 0.92 THRB (0.75) THRB
SCHEMBL5364300 0.90 THRB (0.61) THRB
SCHEMBL5361824 0.89 THRB (0.61) THRB
SCHEMBL5363967 0.88 THRB (0.62) THRB
SCHEMBL5372656 0.85 THRB (0.66) THRB
SCHEMBL17686409 0.83 THRB (0.66) THRB
SCHEMBL5366554 0.83 THRB (0.73) THRB
SCHEMBL5354081 0.82 THRB (0.62) THRB
SCHEMBL5362964 0.81 THRB (0.70) THRB
SCHEMBL8225336 0.81 THRB (0.70) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007140982-A1 SUBSTITUTED BENZOXAZOLES BAYER HEALTHCARE AG (DE) 2007-12-13 WO disclosed
WO-2007140982-A1 SUBSTITUTED BENZOXAZOLES BAYER HEALTHCARE AG (DE) 2007-12-13 WO disclosed