Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730034 | 0.84 | ADRB2 (0.37) | — | |
| SCHEMBL4294692 | 0.73 | ADRB2 (0.39) | TOP2ATOP2B | |
| SCHEMBL729612 | 0.73 | ADRB2 (0.39) | — | |
| SCHEMBL6671328 | 0.71 | EEF2K (0.35) | TOP2ATOP2B | |
| SCHEMBL731267 | 0.71 | ADRB2 (0.40) | TOP2ATOP2B | |
| SCHEMBL2676613 | 0.71 | KCNH2 (0.38) | — | |
| SCHEMBL4300362 | 0.69 | TOP2A (0.39) | TOP2ATOP2B | |
| SCHEMBL727962 | 0.69 | KCNH2 (0.38) | — | |
| SCHEMBL727961 | 0.69 | KCNH2 (0.38) | — | |
| SCHEMBL1984659 | 0.68 | ADRB2 (0.58) | TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414368-A2 | HYDROXYTHIENOQUINOLONES AND RELATED COMPOUNDS AS ANTI-INFECTIVE AGENTS | Achillion Pharmaceuticals, Inc. (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010115184-A2 | HYDROXYTHIENOQUINOLONES AND RELATED COMPOUNDS AS ANTI-INFECTIVE AGENTS | ACHILLION PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | WO | disclosed |