Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 15/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410122 | 0.84 | FAAH (0.65) | FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL14502395 | 0.81 | FAAH (0.61) | FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL5366491 | 0.80 | FAAH (0.76) | FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL14502386 | 0.77 | FAAH (0.79) | FAAH | |
| SCHEMBL4265305 | 0.76 | FAAH (0.79) | FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL4269863 | 0.76 | FAAH (0.79) | FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL4266357 | 0.76 | FAAH (0.79) | FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL4260383 | 0.75 | FAAH (0.82) | FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL4419116 | 0.75 | FAAH (0.82) | FAAHCNR1CNR2PLA2G4A | |
| SCHEMBL14532898 | 0.74 | FAAH (1.00) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39634-E1 | Bisarylimidazoly fatty acid amide hydrolase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-15 | — | — | US | claimed |
| US-RE39634-E1 | Bisarylimidazoly fatty acid amide hydrolase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-15 | — | — | US | disclosed |
| US-RE39634-E1 | Bisarylimidazoly fatty acid amide hydrolase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-15 | — | — | US | disclosed |
| US-RE39634-E1 | Bisarylimidazoly fatty acid amide hydrolase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-15 | — | — | US | disclosed |
| US-6562846-B2 | Bisarylimidazolyl fatty acid amide hydrolase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2003-05-13 | — | — | US | disclosed |