SCHEMBL5370771

SCHEMBL5370771

CC(C)C(NC(=O)CCc1ccc(O)cc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 1/20 0.50
▸ HDAC2 Q92769 1/20 0.50
▸ HDAC8 Q9BY41 1/20 0.50
▸ SDCBP O00560 3/20 0.49
▸ SDC2 P34741 3/20 0.49
▸ GAA P10253 2/20 0.49
▸ ALDH1A1 P00352 2/20 0.49
▸ FNTA P49354 1/20 0.46
▸ FNTB P49356 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.45
▸ HCAR2 Q8TDS4 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ ADAMTS4 O75173 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5711363 0.88 ALDH1A1 (0.56) HDAC2HDAC8SDCBPSDC2ALDH1A1
SCHEMBL6446379 0.88 ALDH1A1 (0.56) HDAC2HDAC8SDCBPSDC2ALDH1A1
SCHEMBL5381881 0.85 ALDH1A1 (0.54) HDAC2HDAC8GAAALDH1A1KDM4E
SCHEMBL26080336 0.84 HRH3 (0.53) HDAC2HDAC8GAAALDH1A1TSHR
SCHEMBL5368224 0.84 IAPP (0.50) HSD17B10SDCBPSDC2GAAALDH1A1
SCHEMBL13602582 0.82 ALDH1A1 (0.69) HSD17B10HDAC2HDAC8GAAALDH1A1
SCHEMBL26005445 0.79 HDAC2 (0.48) HSD17B10HDAC2HDAC8GAAALDH1A1
SCHEMBL26616556 0.79 SMN1; SMN2 (0.67) HDAC2HDAC8GAAALDH1A1FNTA
SCHEMBL9503736 0.79 SMN1; SMN2 (0.67) HDAC2HDAC8GAAALDH1A1FNTA
SCHEMBL13375869 0.78 SMN1; SMN2 (0.61) HDAC2HDAC8GAAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same BIONUTRIGEN CO., LTD. (KR) 2003-10-23 — — US claimed
US-7223793-B2 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same BIONUTRIGEN CO., LTD. (KR) 2007-05-29 — — US disclosed
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same BIONUTRIGEN CO., LTD. (KR) 2003-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same NCEH1, HMGCR, DBH HSD17B10 77/4885HDAC2 391/4885HDAC8 1190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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