SCHEMBL5370832

SCHEMBL5370832

CCCCCCCOC(=O)c1cccc(C(=O)OCCCCCC)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.66
ALDH1A1 P00352 3/20 0.65
TSHR P16473 2/20 0.65
ESR1 P03372 3/20 0.64
NPC1 O15118 1/20 0.64
MAPT P10636 1/20 0.64
RAB9A P51151 1/20 0.64
AKR1C4 P17516 1/20 0.64
AKR1C3 P42330 1/20 0.64
AKR1C2 P52895 1/20 0.64
AKR1C1 Q04828 1/20 0.64
TP53 P04637 1/20 0.62
CYP3A4 P08684 1/20 0.62
MAPK1 P28482 1/20 0.62
TDP1 Q9NUW8 1/20 0.59
CNR2 P34972 1/20 0.58
KDM4E B2RXH2 1/20 0.56
POLB P06746 1/20 0.56
HSD17B10 Q99714 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30019208 1.00 LMNA (0.66) LMNAALDH1A1TSHRESR1NPC1
SCHEMBL5366432 1.00 LMNA (0.66) LMNAALDH1A1TSHRESR1NPC1
SCHEMBL5371920 1.00 LMNA (0.66) LMNAALDH1A1TSHRESR1NPC1
SCHEMBL2535794 1.00 LMNA (0.66) LMNAALDH1A1TSHRESR1NPC1
SCHEMBL19348924 1.00 LMNA (0.66) LMNAALDH1A1TSHRESR1NPC1
SCHEMBL5373212 1.00 LMNA (0.66) LMNAALDH1A1TSHRESR1NPC1
SCHEMBL106401 1.00 LMNA (0.66) LMNAALDH1A1TSHRESR1NPC1
SCHEMBL111221 1.00 LMNA (0.66) LMNAALDH1A1TSHRESR1NPC1
SCHEMBL110817 1.00 LMNA (0.66) LMNAALDH1A1TSHRESR1NPC1
SCHEMBL28975978 1.00 LMNA (0.66) LMNAALDH1A1TSHRESR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US claimed
EP-1194396-B1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AG (DE) 2005-11-09 EP claimed
CN-115216356-A Base oil for fluid dynamic bearing lubricant, fluid dynamic bearing, motor, and fan motor 日本电产株式会社 2022-10-21 CN disclosed
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US disclosed