Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | WDR5 | P61964 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.31 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.31 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.31 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.31 |
| ▸ | ATP4A | P20648 | 2/20 | 0.31 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.31 |
| ▸ | ATP4B | P51164 | 2/20 | 0.31 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.31 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.31 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.31 |
| ▸ | BRS3 | P32247 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369389 | 0.93 | CYP2C9 (0.34) | ENPP2CYP2C9ALDH1A1SMN1; SMN2WDR5 | |
| SCHEMBL5370920 | 0.90 | CYP2C9 (0.36) | ENPP2CYP2C9LPAR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL5368635 | 0.90 | CYP2C9 (0.39) | CYP2C9ALDH1A1SMN1; SMN2WDR5KMT2A | |
| SCHEMBL5358420 | 0.87 | BRS3 (0.44) | ENPP2CYP2C9LPAR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL5763035 | 0.86 | CYP2C9 (0.39) | CYP2C9ALDH1A1SMN1; SMN2WDR5KMT2A | |
| SCHEMBL5369395 | 0.83 | CYP2C9 (0.35) | ENPP2CYP2C9LPAR3ALDH1A1SMN1; SMN2 | |
| Lithium Ion SCHEMBL5367188 | 0.82 | CYP2C9 (0.38) | CYP2C9ALDH1A1SMN1; SMN2WDR5KMT2A | |
| SCHEMBL5360436 | 0.82 | CYP2C9 (0.38) | CYP2C9ALDH1A1SMN1; SMN2WDR5KMT2A | |
| SCHEMBL5366915 | 0.81 | CYP2C9 (0.37) | CYP2C9ALDH1A1SMN1; SMN2WDR5KMT2A | |
| SCHEMBL5358428 | 0.81 | BRS3 (0.46) | ENPP2CYP2C9LPAR3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294716-B2 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALLERGAN, INC. (US) | 2007-11-13 | — | — | US | disclosed |
| US-20050038076-A1 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALEVIUM PHARMACEUTICALS, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038076-A1 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | SI, ATP6AP1, HRH2 | ENPP2 2031/4885CYP2C9 59/4885LPAR3 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.