SCHEMBL5371706

SCHEMBL5371706

C/C(=C\C1(C(=O)OCc2c(F)c(F)c(C)c(F)c2F)CC1(C)C)CO

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
IMPDH2 P12268 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5371713 1.00 MEN1 (0.38) MEN1KMT2ATDP1IMPDH2
SCHEMBL5372585 0.90
SCHEMBL5372594 0.90
SCHEMBL5370110 0.88 IMPDH2 (0.32) IMPDH2
SCHEMBL5370116 0.88 IMPDH2 (0.32) IMPDH2
SCHEMBL5367410 0.85 TDP1 (0.38) MEN1KMT2ATDP1IMPDH2
SCHEMBL5369999 0.85 MEN1 (0.38) MEN1KMT2ATDP1
SCHEMBL5367402 0.85 TDP1 (0.38) MEN1KMT2ATDP1IMPDH2
SCHEMBL5370001 0.85 MEN1 (0.38) MEN1KMT2ATDP1
SCHEMBL5381062 0.78 POLB (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276622-B2 Method for producing oxygen-containing compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-02 US disclosed