Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 13/20 | 0.38 |
| ▸ | PPARG | P37231 | 13/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380793 | 0.89 | FFAR1 (0.52) | FFAR1PPARAPPARGMAPTKDR | |
| SCHEMBL6593508 | 0.88 | FFAR1 (0.42) | FFAR1PPARAPPARGKMT2ASMN1; SMN2 | |
| SCHEMBL6593504 | 0.88 | FFAR1 (0.42) | FFAR1PPARAPPARGKMT2ASMN1; SMN2 | |
| SCHEMBL5374488 | 0.87 | FFAR1 (0.39) | FFAR1PPARAPPARGMAPTSMN1; SMN2 | |
| SCHEMBL4851874 | 0.86 | FFAR1 (0.41) | FFAR1PPARAPPARGUSP2LMNA | |
| SCHEMBL5372013 | 0.86 | FFAR1 (0.39) | FFAR1PPARAPPARGUSP2LMNA | |
| SCHEMBL5397282 | 0.85 | FFAR1 (0.45) | FFAR1PPARAPPARGUSP2LMNA | |
| SCHEMBL4851267 | 0.84 | FFAR1 (0.46) | FFAR1PPARAPPARGUSP2LMNA | |
| SCHEMBL5397552 | 0.83 | FFAR1 (0.48) | FFAR1PPARAPPARGKDR | |
| SCHEMBL5381940 | 0.82 | FFAR1 (0.41) | FFAR1PPARAPPARGKMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179823-B1 | 5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-20 | — | — | US | disclosed |