Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 11/20 | 0.40 |
| ▸ | PPARA | Q07869 | 10/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593508 | 1.00 | FFAR1 (0.42) | FFAR1PPARGPPARAMEN1KMT2A | |
| SCHEMBL5372013 | 0.92 | FFAR1 (0.39) | FFAR1PPARGPPARAKMT2ASMN1; SMN2 | |
| SCHEMBL5374488 | 0.90 | FFAR1 (0.39) | FFAR1PPARGPPARASMN1; SMN2ADORA3 | |
| SCHEMBL4851874 | 0.89 | FFAR1 (0.41) | FFAR1PPARGPPARAKMT2ASMN1; SMN2 | |
| SCHEMBL6591750 | 0.89 | FFAR1 (0.55) | FFAR1PPARGPPARAMEN1KMT2A | |
| SCHEMBL6591759 | 0.89 | FFAR1 (0.55) | FFAR1PPARGPPARAMEN1KMT2A | |
| SCHEMBL4848923 | 0.88 | PPARG (0.45) | FFAR1PPARGPPARAMEN1KMT2A | |
| SCHEMBL4848921 | 0.88 | PPARG (0.45) | FFAR1PPARGPPARAMEN1KMT2A | |
| SCHEMBL5372019 | 0.88 | FFAR1 (0.40) | FFAR1PPARGPPARAKMT2ASMN1; SMN2 | |
| SCHEMBL5397282 | 0.88 | FFAR1 (0.45) | FFAR1PPARGPPARAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457490-A1 | 5-membered N-heterocyclic compounds with hypoglycemic and hypolipidemic activity | Takeda Chemical Industries, Ltd. (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-1228067-B1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-07-14 | — | — | EP | disclosed |