Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420198 | 0.98 | TDP1 (0.63) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| Bicarbonate SCHEMBL27655013 | 0.92 | TDP1 (0.57) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| Bicarbonate SCHEMBL27655012 | 0.92 | TDP1 (0.57) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL28850685 | 0.90 | TDP1 (0.55) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL28174269 | 0.88 | TDP1 (0.53) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL28716126 | 0.87 | ESR1 (0.52) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| Pyrrolidine SCHEMBL27926422 | 0.85 | TDP1 (0.50) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL561869 | 0.85 | TDP1 (0.70) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL17978153 | 0.84 | LMNA (0.50) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL28716128 | 0.84 | TSHR (0.55) | TDP1MAPK1HIF1ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176789-A | Novel amidino-containing iNOS inhibitor with neuroprotection function, and preparation method and application thereof | 中国药科大学 | 2024-12-24 | — | — | CN | claimed |
| CN-113956182-B | HDAC/MAO-B dual inhibitor and preparation and application thereof | 杭州师范大学 | 2023-11-17 | — | — | CN | claimed |
| CN-114621194-B | 4-methylene-N-hydroxybenzoamide compound and application thereof | 沈阳药科大学 | 2023-08-29 | — | — | CN | claimed |
| CN-113956182-A | HDAC/MAO-B dual inhibitor and preparation and application thereof | 杭州师范大学 | 2022-01-21 | — | — | CN | claimed |
| CN-112899688-A | Guanidine-containing benzimidazole corrosion inhibitor and preparation method thereof | 邓万菁 | 2021-06-04 | — | — | CN | claimed |
| CN-102234266-B | Preparation and application of tetrahydrofolic acid ring-opened analogs with aziridine structure | UNIV BEIJING | 2013-12-18 | — | — | CN | claimed |
| US-20110091957-A1 | PROTEIN-POLYMER CONJUGATES AND SYNTHESIS THEREOF | PITTSBURGH, UNIVERSITY OF - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2011-04-21 | — | — | US | claimed |
| US-20070123646-A1 | Protein-polymer conjugates and synthesis thereof | PITTSBURGH, UNIVERSITY OF | 2007-05-31 | — | — | US | claimed |
| CN-1275989-C | Water-soluble poly-p-phenylene ethynylene and synthetic method | UNIV FUDAN (CN) | 2006-09-20 | — | — | CN | claimed |
| CN-1600796-A | Water-soluble poly-p-phenylene ethynylene and synthetic method | UNIV FUDAN (CN) | 2005-03-30 | — | — | CN | claimed |
| US-6086764-A | Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use | CROSSWINDS, INC. (US) | 2000-07-11 | — | — | US | claimed |
| EP-0884096-A1 | Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use | Crosswinds, Inc. (US) | 1998-12-16 | — | — | EP | claimed |
| CN-119912442-A | 2, 4-Disubstituted thiadiazole derivatives and their use as GLS1 inhibitors | 四川大学华西医院 | 2025-05-02 | — | — | CN | disclosed |
| CN-119768881-A | Method for producing a polymer capacitor, conductive polymer composition and use thereof as a conductive layer in an electronic component | 爱克发-格法特公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2025038747-A1 | MODIFIED THIOSTREPTON-INSPIRED COMPOUNDS FOR TREATMENT OF CANCER AND PREPARATION THEREOF | RS ONCOLOGY, LLC (US) | 2025-02-20 | — | — | WO | disclosed |
| CN-119176789-A | Novel amidino-containing iNOS inhibitor with neuroprotection function, and preparation method and application thereof | 中国药科大学 | 2024-12-24 | — | — | CN | disclosed |
| EP-0178775-B1 | FLUORESCENT INDICATOR DYES FOR CALCIUM IONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1988-11-09 | — | — | EP | disclosed |
| US-4603209-A | STILBENE-TYPE FLUOROPHORE, TWO AMINODIACETIC ACID MOIETIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1986-07-29 | — | — | US | disclosed |
| EP-0178775-A2 | Fluorescent indicator dyes for calcium ions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1986-04-23 | — | — | EP | disclosed |
| US-4258196-A | REACTING THE ANION OF A PRIMARY OR SECONDARY 2-HALOACETAMIDE WITH AN ALKYLATING AGENT | MONSANTO COMPANY (US) | 1981-03-24 | — | — | US | disclosed |