⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191599 | 0.75 | LAP3 (0.38) | — | |
| SCHEMBL7179882 | 0.74 | — | — | |
| SCHEMBL919194 | 0.73 | — | — | |
| SCHEMBL94328 | 0.72 | — | — | |
| SCHEMBL94341 | 0.72 | — | — | |
| SCHEMBL27313311 | 0.72 | — | — | |
| SCHEMBL27495089 | 0.72 | — | — | |
| SCHEMBL10831667 | 0.70 | KDM4E (0.40) | — | |
| Oxidronic Acid SCHEMBL393281 | 0.70 | KDM4E (0.40) | — | |
| Oxidronic Acid SCHEMBL29363818 | 0.67 | KDM4E (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4615977-A | AMINE DERIVATIVES PROMOTE GROWTH WITH LOW SERUM CONCENTRATIONS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-10-07 | — | — | US | claimed |
| EP-0082974-B1 | METHOD FOR THE CULTIVATION OF NORMAL DIPLOID CELLS AND CULTIVATION MEDIUM USED THEREFOR | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-05-14 | — | — | EP | claimed |
| EP-0082974-A2 | Method for the cultivation of normal diploid cells and cultivation medium used therefor | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-07-06 | — | — | EP | claimed |
| CN-103781783-A | Piperazine-substituted benzothiophene derivatives as antipsychotic agents | OTSUKA PHARMA CO LTD | 2014-05-07 | — | — | CN | disclosed |
| US-7244718-B2 | Water soluble prodrugs of hindered alcohols | UNIVERSITY OF KANSAS (US) | 2007-07-17 | — | — | US | disclosed |
| EP-1683803-A1 | Water soluble prodrugs of hindered alcohols or phenols | THE UNIVERSITY OF KANSAS (US) | 2006-07-26 | — | — | EP | disclosed |
| CN-1809557-A | Compound | ASTRAZENECA AB (SE) | 2006-07-26 | — | — | CN | disclosed |
| EP-1102776-B1 | WATER SOLUBLE PRODRUGS OF HINDERED PHENOLS | UNIV KANSAS (US) | 2006-03-08 | — | — | EP | disclosed |
| US-20050090431-A1 | Water soluble prodrugs of hindered alcohols | UNIVERSITY OF KANSAS (US) | 2005-04-28 | — | — | US | disclosed |
| EP-1102776-A1 | WATER SOLUBLE PRODRUGS OF HINDERED ALCOHOLS OR PHENOLS | THE UNIVERSITY OF KANSAS (US) | 2001-05-30 | — | — | EP | disclosed |
| US-6204257-B1 | Water soluble prodrugs of hindered alcohols | UNIVERSTIY OF KANSAS | 2001-03-20 | — | — | US | disclosed |
| WO-1996040155-A1 | USE OF SPECIFIC ACPA DERIVATIVE (NPC-17742) FOR THE TREATMENT OF ISCHEMIA | THE JOHNS HOPKINS UNIVERSITY (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0639197-B1 | EXCITATORY AMINO ACID ANTAGONISTS | GUILFORD PHARM INC (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0639197-A1 | EXCITATORY AMINO ACID ANTAGONISTS. | GUILFORD PHARM INC (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0639197-A4 | EXCITATORY AMINO ACID ANTAGONISTS. | GUILFORD PHARM INC (US) | 1994-02-21 | — | — | EP | disclosed |
| US-5256814-A | Anticonvulsant, analgesic, cognition activator | SCIOS NOVA INC. (US) | 1993-10-26 | — | — | US | disclosed |
| WO-1992010099-A1 | EXCITATORY AMINO ACID ANTAGONISTS | NOVA PHARMACEUTICAL CORPORATION (US) | 1992-06-25 | — | — | WO | disclosed |
| US-4615977-A | AMINE DERIVATIVES PROMOTE GROWTH WITH LOW SERUM CONCENTRATIONS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0082974-B1 | METHOD FOR THE CULTIVATION OF NORMAL DIPLOID CELLS AND CULTIVATION MEDIUM USED THEREFOR | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0082974-A2 | Method for the cultivation of normal diploid cells and cultivation medium used therefor | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-07-06 | — | — | EP | disclosed |