Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 7/20 | 0.51 |
| ▸ | HPRT1 | P00492 | 9/20 | 0.50 |
| ▸ | XDH | P47989 | 5/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TK1 | P04183 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840727 | 0.87 | XDH (0.50) | PNPHPRT1XDHUSP2TSHR | |
| SCHEMBL663747 | 0.87 | HPRT1 (0.55) | PNPHPRT1USP2TSHREDNRA | |
| SCHEMBL27947874 | 0.86 | HPRT1 (0.54) | PNPHPRT1 | |
| Ammonia Solution, Strong SCHEMBL27860602 | 0.85 | HPRT1 (0.53) | PNPHPRT1 | |
| SCHEMBL28286406 | 0.84 | PNP (0.36) | PNPHPRT1XDHUSP2TSHR | |
| SCHEMBL27758688 | 0.84 | HPRT1 (0.52) | PNPHPRT1 | |
| SCHEMBL15948931 | 0.83 | HPRT1 (0.51) | PNPHPRT1XDHUSP2TSHR | |
| SCHEMBL22434502 | 0.83 | HPRT1 (0.51) | PNPHPRT1XDH | |
| SCHEMBL22434709 | 0.83 | XDH (0.49) | PNPHPRT1XDHUSP2TSHR | |
| SCHEMBL101894 | 0.83 | PNP (0.61) | PNPHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217523-B2 | Nucleoside phosphoramidates and nucleoside phosphoramidases | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-05-15 | — | — | US | claimed |
| US-20060014193-A1 | Nucleoside phosphoramidates and nucleoside phosphoramidases | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2006-01-19 | — | — | US | claimed |
| US-7217523-B2 | Nucleoside phosphoramidates and nucleoside phosphoramidases | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-05-15 | — | — | US | disclosed |
| US-20060014193-A1 | Nucleoside phosphoramidates and nucleoside phosphoramidases | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2006-01-19 | — | — | US | disclosed |