SCHEMBL537276

SCHEMBL537276

CCN(CC)c1ccc(-c2ccccc2C(=O)O)c(O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.68
KMT2A Q03164 6/20 0.68
SMN1; SMN2 Q16637 4/20 0.68
L3MBTL1 Q9Y468 2/20 0.68
ALDH1A1 P00352 7/20 0.52
KDM4E B2RXH2 4/20 0.52
GAA P10253 4/20 0.52
POLB P06746 1/20 0.52
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
NOX1 Q9Y5S8 1/20 0.48
MAPT P10636 6/20 0.47
FOLH1 Q04609 1/20 0.47
HPGD P15428 3/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
SLC16A3 O15427 1/20 0.46
ALOX15 P16050 1/20 0.46
SLC16A1 P53985 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39206 0.81 KMT2A (1.00) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL503775 0.81 MEN1 (0.75) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL537275 0.79 MEN1 (0.64) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL9762350 0.79 MEN1 (0.59) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL1520808 0.78 MEN1 (0.61) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL6382798 0.78 TSHR (0.58) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL11369420 0.77 MEN1 (0.78) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL22939383 0.77 MEN1 (0.82) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL27913467 0.77 MEN1 (0.89) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL17288014 0.77 KMT2A (0.61) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2413691-A2 METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS BASF SE (DE) 2012-02-08 EP claimed
WO-2010115721-A2 METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS BASF SE (DE) 2010-10-14 WO claimed
US-20090220442-A1 SUNSCREEN COMPOSITION COMPRISING A DIBENZOYLMETHANE, AN AMINOHYDROXYBENZOPHENONE, A TRIAZINE AND A TRIAZOLE AS UV FILTERS JOHNSON & JOHNSON CONSUMER FRANCE, S.A.S. (FR) 2009-09-03 US claimed
EP-1928401-A1 SUNSCREEN COMPOSITION COMPRISING A DIBENZOYLMETHANE, AN AMINOHYDROXYBENZOPHENONE, A TRIAZINE AND A TRIAZOLE AS UV FILTERS Johnson & Johnson Consumer France SAS (FR) 2008-06-11 EP claimed
EP-1764081-A1 Sunscreen composition comprising a dibenzoylmethane, an aminohydroxybenzophenone, a triazine and a triazole as UV filters Johnson & Johnson Consumer France SAS (FR) 2007-03-21 EP claimed
WO-2007025599-A1 SUNSCREEN COMPOSITION COMPRISING A DIBENZOYLMETHANE, AN AMINOHYDROXYBENZOPHENONE, A TRIAZINE AND A TRIAZOLE AS UV FILTERS JOHNSON & JOHNSON CONSUMER FRANCE S.A.S. (FR) 2007-03-08 WO claimed
US-20090220442-A1 SUNSCREEN COMPOSITION COMPRISING A DIBENZOYLMETHANE, AN AMINOHYDROXYBENZOPHENONE, A TRIAZINE AND A TRIAZOLE AS UV FILTERS JOHNSON & JOHNSON CONSUMER FRANCE, S.A.S. (FR) 2009-09-03 US disclosed
EP-1928401-A1 SUNSCREEN COMPOSITION COMPRISING A DIBENZOYLMETHANE, AN AMINOHYDROXYBENZOPHENONE, A TRIAZINE AND A TRIAZOLE AS UV FILTERS Johnson & Johnson Consumer France SAS (FR) 2008-06-11 EP disclosed
EP-1764081-A1 Sunscreen composition comprising a dibenzoylmethane, an aminohydroxybenzophenone, a triazine and a triazole as UV filters Johnson & Johnson Consumer France SAS (FR) 2007-03-21 EP disclosed
WO-2007025599-A1 SUNSCREEN COMPOSITION COMPRISING A DIBENZOYLMETHANE, AN AMINOHYDROXYBENZOPHENONE, A TRIAZINE AND A TRIAZOLE AS UV FILTERS JOHNSON & JOHNSON CONSUMER FRANCE S.A.S. (FR) 2007-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090220442-A1 SUNSCREEN COMPOSITION COMPRISING A DIBENZOYLMETHANE, AN AMINOHYDROXYBENZOPHENONE, A TRIAZINE AND A TRIAZOLE AS UV FILTERS CDC73, CUTA, TYR MEN1 3483/4885KMT2A 3328/4885SMN1; SMN2 4851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.